buncha meds Flashcards

1
Q

nimodipine (Nimotop)

MOA only

A

MOA: CCB - counters vasospasms by preventing Ca from entering smooth muscle cells + causing contraction (CVA)

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2
Q

ticlopidine (Ticlid)

A

MOA: anti-platelet

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3
Q

ticlopidine considerations

A

aka Ticlid

AE: assoc w agranulocytosis, thrombotic thrombocytopenia purpura, GI intolerance

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4
Q

pyridostigmine (Prostigmin)

A

MOA: anticholinesterase - block hydrolysis of ACh
indication: symptomatic improvement in myasthenia gravis

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5
Q

edrophonium (Tensilon)

A

MOA: ultra short-acting AChE inhbitor
indication: distinguish between myasthenia crisis & cholinergic crisis

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6
Q

carbidopa-levodopa (Sinemet)

A

MOA: increase available dopamine
indication: Parkinson’s Disease mgmt

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7
Q

amantadine (Symmetryl)

A

MOA: increase available dopamine
indication: Parkinson’s Disease mgmt

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8
Q

pramipexole (Mirapex)

A

MOA: increase available dopamine
indication: Parkinson’s Disease mgmt

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9
Q

ropinirole (Requip)

A

MOA: increase available dopamine
indication: Parkinson’s Disease mgmt

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10
Q

benztropine (Cogentin)

A

MOA: anticholinergic (alleviate tremor, rigidity)
indication: Parkinson’s Disease mgmt

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11
Q

trihexyphenyldyl (Artane)

A

MOA: anticholinergic (alleviate tremor, rigidity)
indication: Parkinson’s Disease mgmt

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12
Q

donepezil (Aricept) = memory improvement

A

MOA: acetylcholinesterase inhibitor
indication: Alzheimer’s (specifically, memory improvement)

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13
Q

rivastigmine (Exelon)

A

MOA: acetylcholinesterase inhibitor
indication: Alzheimer’s

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14
Q

albuterol (Proventil)

A

MOA: short-acting beta-2 adrenergic agonist (SABA), bronchodilates
indication: asthma rescue, sx relief/breakthrough, or pre-exercise; or inpt mgmt

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15
Q

budesonide (Pulmicort)

A

MOA: inhaled corticosteroid
indication: daily maintenance tx for asthma + increase if sx persist

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16
Q

triamcinolone (Azmacort)

A

MOA: inhaled corticosteroid
indication: daily maintenance tx for asthma + increase if sx persist

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17
Q

salmeterol (Serevent)

A

MOA: long-acting beta-2 adrenergic agonist (LABA)
indication: persistent asthma symptoms

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18
Q

ipratropium bromide (Atrovent)

A

MOA: inhaled anticholinergic
indication: asthma adjunct for secretion mgmt, also inpt mgmt

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19
Q

montelukast (Singulair)

A

MOA: antileukotriene
indication: chronic asthma - stabilization

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20
Q

alupent

A

MOA: inhalation sympathomimetic
indication: inpt mgmt of asthma

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21
Q

methylprednisolone 60 - 125 mg IV

A

MOA: corticosteroid
indication: inpt mgmt of asthma for pts who do not respond to sympathomimetics

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22
Q

aqueous epinephrine 1:1000 0.1 - 0.5 mL SQ

A

MOA: parenteral sympathomimetic
indication: asthma tx for inpt unable to cooperate

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23
Q

TB drug doses

A

Rifampin 600 mg
Isoniazid 300 mg
Pyrazinamide 1.5 - 2.0 g
Ethambutol 15 mg/kg

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24
Q

hydrocodone-APAP: generic for which 2 brands

A

Vicodin, Lortab

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25
Q

amitriptyline (Elavil) class x2

A

antidepressant & neuropathic pain

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26
Q

sumatriptan (Imitrex)

A

MOA: triptan, 5-HT agonist
uses: acute migraine

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27
Q

acetazolamide (Diamox)

A

MOA: carbonic anhydrase inhibitor, inhibits renal tubule H+ excretion (increases Na, K, bicarb, H2O excretion) producing alkaline diuresis
uses: metabolic alkalosis

28
Q

dantrolene sodium (Dantrium) is a treatment for

A

Serotonin Syndrome

29
Q

diazepam

A

Valium

30
Q

lorazepam

A

Ativan

31
Q

midazolam

A

Versed

32
Q

butorphanol (Stadol) use

A

opioid toxicity reversal

33
Q

flumazenil (Romazicon) use

A

benzo toxicity reversal

34
Q

calcineurin inhibitors x2

A

tacrolimus (Prograft)
cyclosporine

can use for transplant rejection prophylaxis

35
Q

antimetabolites x 2

A
azathioprine (Imuran)
mycophenolate mofetil (Cellcept)

can use for transplant rejection prophylaxis

36
Q

glipizide (Glucotrol)

A

MOA: sulfonylurea - stimulate pancreas to release more insulin
indication: diabetic oral agent

37
Q

glyburide (Diabeta)

A

MOA: sulfonylurea - stimulate pancreas to release more insulin
indication: diabetic oral agent

38
Q

glimepiride (Amaryl)

A

MOA: sulfonylurea - stimulate pancreas to release more insulin
indication: diabetic oral agent

39
Q

acarbose (Precose)

A

MOA: alpha-glucosidase inhibitor - bind to disaccharidases more readily than sucrose, therefore less glucose absorbed by gut
indication: oral antidiabetic

40
Q

miglitol (Glyset)

A

MOA: alpha-glucosidase inhibitor - bind to disaccharidases more readily than sucrose, therefore less glucose absorbed by gut
indication: oral antidiabetic

41
Q

rosiglitazone maleate (Avandia)

A

MOA: “glitazone” - decrease gluconeogenesis
indication: oral antidiabetic

42
Q

pioglitazone hydrochloride (Actos)

A

MOA: “glitazone” - decrease gluconeogenesis
indication: oral antidiabetic

43
Q

repaglinide (Prandin)

A

MOA: non-sulfonylurea insulin release stimulator - rapidly abs from intestine & mimics effect of rapid-acting insulin
indication: indication: oral antidiabetic

44
Q

nateglinide (Starlix)

A

MOA: non-sulfonylurea insulin release stimulator - rapidly abs from intestine & mimics effect of rapid-acting insulin
indication: indication: oral antidiabetic

45
Q

ACE inhibitor MOA*

A

block RAAS system @ angiotensin II

46
Q

thiazide diuretics MOA*

A

⊣ reabs Na + Cl in distal tubule → ↑ urinary excretion Na + H2O

Direct arteriolar vasodilation.

47
Q

loop diuretics MOA*

A

K EXCRETED

⊣ reabs Na + Cl in proximal + distal tubules + loop of Henle (Na-K-Cl co-transporter = K reabs)

interferes with Cl-binding cotransport system, → ↑ excretion Na, H2O, Ca, Mg, Cl

48
Q

spironolactone MOA*

A

K SPARED

competes with aldosterone @ distal tubule receptors

↑ Na Cl + H2O excretion while conserving K + H

49
Q

diltiazem class

A

CCB

50
Q

amlodipine class

A

CCB

51
Q

prazosin (Minipress)

A

MOA: alpha-1 antagonist - causes vasodilation
indication: BPH, htn adjunct

52
Q

terazosin (Hytrin)

A

MOA: alpha-1 antagonist - causes vasodilation
indication: BPH, htn adjunct

53
Q

doxazosin (Cardura)

A

MOA: alpha-1 antagonist - causes vasodilation
indication: BPH, htn adjunct

54
Q

clonidine (Catapres)

A

MOA: central alpha-2 agonist - prevents vasoconstriction, causes vasodilation, negative chronotrope
indication: hypertension adjunct

55
Q

methyldopa (Aldomet)

A

MOA: central alpha-2 agonist - prevents vasoconstriction, causes vasodilation, negative chronotrope
indication: hypertension adjunct

56
Q

minodixil (Loniten)

A

MOA: arterial vasodilator - directly relaxes vascular smooth muscle → arterial vasodilation
indication: hypertension adjunct

57
Q

aliskiren (Tekturna)

A

MOA: direct renin inhibitor - inhibits renin = ↓ plasma renin activity as well as conversion of angiotensinogen I to angiotensin I
indication: hypertension, but avoid because it doesn’t offer advantages compared with others, is expensive, and is a teratogen

58
Q

nifedipine class

A

CCB

59
Q

nicardipine (Cardene) class

A

CCB

60
Q

verapamil class

A

CCB

61
Q

diltiazem class

A

CCB

62
Q

cholestyramine (Questran)

A

MOA: bile acid sequestrant - mostly ↓ LDL + may ↑ trigs
indication: lipid mgmt for angina tx

63
Q

colesevelam (Welchol)

A

MOA: bile acid sequestrant - mostly ↓ LDL + may ↑ trigs
indication: lipid mgmt for angina tx

64
Q

colestipol (Colestid)

A

MOA: bile acid sequestrant - mostly ↓ LDL + may ↑ trigs
indication: lipid mgmt for angina tx

65
Q

gemfibrozil (Lopid)

A

MOA: fibrate
indication: lipid mgmt for angina tx

66
Q

fenofibrate (Tricor)

A

MOA: fibrate
indication: lipid mgmt for angina tx

67
Q

ezetimibe (Zetia)

A

MOA: cholesterol absorption inhibitor
indication: use in combo + statin to ↓ LDL