Bugs and drugs (DOC for infections) Flashcards
S. aureus (food poisoning)
NONE (remember, it’s a toxin in this case)
S. aureus (toxic shock syndrome)
Clindamycin + nafcillin, oxacillin
S. aureus (skin and soft tissue infections)
Nafcillin, oxacillin, cefazolin
S. aureus (endocarditis, pneumonia, osteomyelitis, septic arthritis, meningitis)
Nafcillin or oxacillin
MRSA
Vancomycin
Staph epi (most likely case is endocarditis on prosthetic valve/other implants)
Vancomycin
S. saprophyticus
TMP-SMX
S. pyogenes (necrotizing fasciitiss)
IV PenG
S. pyogenes (strep throat)
PenV
S. pyogenes (rheumatic fever)
ORAL PenV
S. pyogenes (PS glomerulonephritis)
Penicillin
S. pyogenes (Scarlet fever)
IM benzathine PenG
S. pyogenes (pyoderma(skin infection))
Penicillin
Take home message; if pt has S. pyo infection, give what?
Some form of penicillin
Strep viridans
PenG
Strep mutans
PenG
S. pneumo (pneumonia)
Beta-lactam for penicillin sensitive strep
S. pneumo (meningitis)
Ceftriaxone + vanco
S. pneumo (otitis media and sinusitis)
amoxicillin
S. agalactiae (most commonly neonatal meningitis presentation)
PenG
Enterococci (UTI)
Ampicillin
Enterococci (endocarditis)
PenG or ampicillin + gentamicin
Actinomyces
Penicillin
Bacillus anthracis (cutaneous)
Ciprofloxacin or doxy
Bacillus anthracis (inhalation)
Cipro+rifampin+vanco
Bacillus cereus
None (intoxication)
Clostridium botulinum
Antiobiotics are contraindicated in infection; you will release more toxin into the body and make things worse
Clostridium perfringens
Penicillin + clindamycin or tetracycline
Clostridium tetani
Metronidazole
Corynebacterium diptheriae
Erythromycin or PenG
Gardnerella vaginalis
Metronidazole
Listeria monocytogenes (neonatal meningitis)
Ampicillin or PenG
Listeria monocytogenes (pregnancy)
Ampicillin
Listeria monocytogenes (gastroenteritis w/ fever)
Ampicillin or TMP-SMX
Mycobacterium avium complex
Clarithromycin or azithromycin
Nocardia
TMP-SMX
N. gonorrhea
Ceftriaxone + azithromycin for possible coexisting chlamydia
N. meningitidis
Ceftriaxone
Basically, if someone has listeria, your go to is…
Ampicillin
Moraxella cattharalis
Amoxicillin
Kleb pneumo
Cephalosporing +/- aminoglycoside
ETEC
Ciprofloxacin (if warranted)
EHEC
NONE; contraindicated, may release more toxin
HUS from EHEC
Eculizumab
EIEC
Fluoroquinolone (if warranted)
E. coli meningitis
3rd gen cephalosporin (ceftriaxone)
E. coli pneumonia
3rd-gen ceph or fluoroquinolone
E. coli UTI
Fluoroquinolone, TMP-SMX, nitrofurantoin
Salmonella (notyphoidal)
Fluoroquinolone
Salmonella (typhoidal)
Fluoroquinolone (adult), ceftriaxone (kid)