Bugs and drugs (DOC for infections) Flashcards

1
Q

S. aureus (food poisoning)

A

NONE (remember, it’s a toxin in this case)

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2
Q

S. aureus (toxic shock syndrome)

A

Clindamycin + nafcillin, oxacillin

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3
Q

S. aureus (skin and soft tissue infections)

A

Nafcillin, oxacillin, cefazolin

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4
Q

S. aureus (endocarditis, pneumonia, osteomyelitis, septic arthritis, meningitis)

A

Nafcillin or oxacillin

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5
Q

MRSA

A

Vancomycin

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6
Q

Staph epi (most likely case is endocarditis on prosthetic valve/other implants)

A

Vancomycin

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7
Q

S. saprophyticus

A

TMP-SMX

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8
Q

S. pyogenes (necrotizing fasciitiss)

A

IV PenG

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9
Q

S. pyogenes (strep throat)

A

PenV

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10
Q

S. pyogenes (rheumatic fever)

A

ORAL PenV

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11
Q

S. pyogenes (PS glomerulonephritis)

A

Penicillin

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12
Q

S. pyogenes (Scarlet fever)

A

IM benzathine PenG

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13
Q

S. pyogenes (pyoderma(skin infection))

A

Penicillin

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14
Q

Take home message; if pt has S. pyo infection, give what?

A

Some form of penicillin

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15
Q

Strep viridans

A

PenG

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16
Q

Strep mutans

A

PenG

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17
Q

S. pneumo (pneumonia)

A

Beta-lactam for penicillin sensitive strep

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18
Q

S. pneumo (meningitis)

A

Ceftriaxone + vanco

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19
Q

S. pneumo (otitis media and sinusitis)

A

amoxicillin

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20
Q

S. agalactiae (most commonly neonatal meningitis presentation)

A

PenG

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21
Q

Enterococci (UTI)

A

Ampicillin

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22
Q

Enterococci (endocarditis)

A

PenG or ampicillin + gentamicin

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23
Q

Actinomyces

A

Penicillin

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24
Q

Bacillus anthracis (cutaneous)

A

Ciprofloxacin or doxy

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25
Q

Bacillus anthracis (inhalation)

A

Cipro+rifampin+vanco

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26
Q

Bacillus cereus

A

None (intoxication)

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27
Q

Clostridium botulinum

A

Antiobiotics are contraindicated in infection; you will release more toxin into the body and make things worse

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28
Q

Clostridium perfringens

A

Penicillin + clindamycin or tetracycline

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29
Q

Clostridium tetani

A

Metronidazole

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30
Q

Corynebacterium diptheriae

A

Erythromycin or PenG

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31
Q

Gardnerella vaginalis

A

Metronidazole

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32
Q

Listeria monocytogenes (neonatal meningitis)

A

Ampicillin or PenG

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33
Q

Listeria monocytogenes (pregnancy)

A

Ampicillin

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34
Q

Listeria monocytogenes (gastroenteritis w/ fever)

A

Ampicillin or TMP-SMX

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35
Q

Mycobacterium avium complex

A

Clarithromycin or azithromycin

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36
Q

Nocardia

A

TMP-SMX

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37
Q

N. gonorrhea

A

Ceftriaxone + azithromycin for possible coexisting chlamydia

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38
Q

N. meningitidis

A

Ceftriaxone

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39
Q

Basically, if someone has listeria, your go to is…

A

Ampicillin

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40
Q

Moraxella cattharalis

A

Amoxicillin

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41
Q

Kleb pneumo

A

Cephalosporing +/- aminoglycoside

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42
Q

ETEC

A

Ciprofloxacin (if warranted)

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43
Q

EHEC

A

NONE; contraindicated, may release more toxin

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44
Q

HUS from EHEC

A

Eculizumab

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45
Q

EIEC

A

Fluoroquinolone (if warranted)

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46
Q

E. coli meningitis

A

3rd gen cephalosporin (ceftriaxone)

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47
Q

E. coli pneumonia

A

3rd-gen ceph or fluoroquinolone

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48
Q

E. coli UTI

A

Fluoroquinolone, TMP-SMX, nitrofurantoin

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49
Q

Salmonella (notyphoidal)

A

Fluoroquinolone

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50
Q

Salmonella (typhoidal)

A

Fluoroquinolone (adult), ceftriaxone (kid)

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51
Q

Pseudomonas (endocarditis, bacteremia)

A

Aminoglycoside +antipseudomonal b-lactam

52
Q

What are the antipseudomonal beta-lactams

A

piperacillin, ticarcillin, ceftazidime, cefepime, imipenem)

53
Q

Pseudomonas (meningitis)

A

Ceftazidime

54
Q

Pseudomonas (Osteomyelitis)

A

Beta-lactam, carbapenem, fluoroquinolone

55
Q

Pseudomonas (UTI)

A

Aminoglycoside or fluoroquinolone

56
Q

Pseudomonas (pneumonia)

A

Antispeudomonal b-lactam, antipseudomonal quinolone+aminoglycoside

57
Q

Vibrios

A

Fluid+electrolytes

58
Q

Campylobacter

A

Fluoroquinolone or azithromycin

59
Q

H. pylori

A

PPI+amoxicillin+clarithromycin

60
Q

H. influenzae (otitis media)

A

Amoxicillin)

61
Q

H. influenza (meningitis)

A

Ceftriaxone

62
Q

Yersinia pestis

A

Streptomycin (gentamycin)

63
Q

Bordatella pertussis

A

Macrolide (historically erythromycin)

64
Q

Pasteurella multocida

A

Amoxicillin-clavulanate

65
Q

Francisella tularensis

A

Streptomycin (or gentamycin)

66
Q

Legionella

A

Levofloxacin (L for L)

67
Q

Brucella

A

Doxy + streptomycin

68
Q

Bacteroides

A

Metronidazle

69
Q

HACEK (causing endocarditis)

A

Ceftriaxone

70
Q

Mycoplasma pneumoniae

A

Macrolide or doxy

71
Q

For all Chlamydia trachomatis infections, give what else besides the DOC

A

Ceftriaxone for possible coinfection with gonorrhea

72
Q

Chlamydia trachomatis (NGU)

A

Azithromycin or doxycycline

73
Q

Chlamydia trachomatis (neonatal conjuctivitis or pneumonia)

A

Erythromycin

74
Q

Chlamydia trachomatis (LGV)

A

Doxycycline

75
Q

Chlamydia trachomatis (Reactive arthritis)

A

NSAIDs

76
Q

Chlamydophila pneumoniae

A

Macrolide if 8

77
Q

Chlamydophila psittaci

A

Doxycycline

78
Q

Treponema pallidum

A

Penicillin

79
Q

Neurosyphillis

A

PenG

80
Q

Leptospira

A

Doxy

81
Q

Ricketsial diseases

A

Doxy for all (even in kids!)

82
Q

Allergic aspergillosis

A

Corticosteroids

83
Q

Aspergilloma (fungal ball)

A

Surgerize it

84
Q

Systemic aspergilllosis

A

Voriconazole

85
Q

Blastomyces dermatiditis

A

Amphoterecin B

86
Q

Candida causing endocarditis, endopthalmitis

A

Amphotericin B (+flucytosine if endocarditis)

87
Q

Candid causing esophageal candidiasis, oral candidiasis (AIDs pt), or peritonitis

A

Fluconazole

88
Q

Oral candidiasis in non-AIDs pts

A

Nystatin

89
Q

Candida causing pneumonia, septic arthritis, osteomyelitis, or UTI

A

Fluconazole OR ampho B

90
Q

Vulvovaginal candidiasis

A

Topical azoles

91
Q

Coccidiodes immitis (pulmonary)

A

Fluconazole

92
Q

Coccidioides immitis (meningitis)

A

Ampho B for 4-6 weeks then azoles

93
Q

Tinea capitis

A

Griseofulvin

94
Q

Tinea pedis, corporis, cruris

A

Topical antifungal

95
Q

Fusarium spp.

A

Topical natamycin

96
Q

Histoplasma

A

Ampho B

97
Q

Mucomycoses

A

Ampho B

98
Q

Paracoccidiodes

A

Itraconazole

99
Q

Pneumocytis jiroveci

A

TMP-SMX

100
Q

Sporothrix schenckii (Rose gardener dx)

A

Itraconazole

101
Q

Sporothrix schenckii (invasive)

A

Ampho B

102
Q

Babesia microti

A

Clindamycin plus quinine

103
Q

Cryptosporidium parvum

A

Nitazoxanide

104
Q

Cyclospora cayetenensis

A

TMP-SMX

105
Q

Entamoeba histolytic

A

Metronidazole

106
Q

Giardia

A

Metro

107
Q

Isospora

A

TMP-SMX

108
Q

Microsporidia

A

Albendazole or umagillin

109
Q

Naegleria fowleri

A

Amphotericin B + rifampin

110
Q

Plasmodium falciparum (malaria)

A

Chloroquine

111
Q

Plasmodium falciparum (cerebral malaria)

A

IV quinine

112
Q

Plasmodium vivax

A

Chloroquine + primaquine

113
Q

Toxoplasma gondii

A

Pyramethamine + sulfadiazine

114
Q

Trichomonas

A

Metro

115
Q

T. cruzi

A

Benznidazole

116
Q

Ascaris lumbricoides (roundworm)

A

Albendazole

117
Q

Enterobius vermicularis (pinworm)

A

Mebendazole

118
Q

Loa loa (eye worm)

A

Diethylcarbamazine

119
Q

Wucheria bancrofti (filiriasis)

A

Diethylcarbazine

120
Q

Fasciola hepatica (Sheep liver fluke)

A

Bithionol

121
Q

Shistosoma haematobium (hematuria)

A

Praziquantel

122
Q

Shistosoma mansoni (bloody poo)

A

Prazi

123
Q

Diphyllobothrium latum (fish tapeworm)

A

Niclosamide

124
Q

Echinococus (hydatid cyst dx)

A

Al or mebendazole

125
Q

Taenia saginata and taenia solium

A

Prazi