Bugs and drugs (DOC for infections) Flashcards
1
Q
S. aureus (food poisoning)
A
NONE (remember, it’s a toxin in this case)
2
Q
S. aureus (toxic shock syndrome)
A
Clindamycin + nafcillin, oxacillin
3
Q
S. aureus (skin and soft tissue infections)
A
Nafcillin, oxacillin, cefazolin
4
Q
S. aureus (endocarditis, pneumonia, osteomyelitis, septic arthritis, meningitis)
A
Nafcillin or oxacillin
5
Q
MRSA
A
Vancomycin
6
Q
Staph epi (most likely case is endocarditis on prosthetic valve/other implants)
A
Vancomycin
7
Q
S. saprophyticus
A
TMP-SMX
8
Q
S. pyogenes (necrotizing fasciitiss)
A
IV PenG
9
Q
S. pyogenes (strep throat)
A
PenV
10
Q
S. pyogenes (rheumatic fever)
A
ORAL PenV
11
Q
S. pyogenes (PS glomerulonephritis)
A
Penicillin
12
Q
S. pyogenes (Scarlet fever)
A
IM benzathine PenG
13
Q
S. pyogenes (pyoderma(skin infection))
A
Penicillin
14
Q
Take home message; if pt has S. pyo infection, give what?
A
Some form of penicillin
15
Q
Strep viridans
A
PenG
16
Q
Strep mutans
A
PenG
17
Q
S. pneumo (pneumonia)
A
Beta-lactam for penicillin sensitive strep
18
Q
S. pneumo (meningitis)
A
Ceftriaxone + vanco
19
Q
S. pneumo (otitis media and sinusitis)
A
amoxicillin
20
Q
S. agalactiae (most commonly neonatal meningitis presentation)
A
PenG
21
Q
Enterococci (UTI)
A
Ampicillin
22
Q
Enterococci (endocarditis)
A
PenG or ampicillin + gentamicin
23
Q
Actinomyces
A
Penicillin
24
Q
Bacillus anthracis (cutaneous)
A
Ciprofloxacin or doxy
25
Bacillus anthracis (inhalation)
Cipro+rifampin+vanco
26
Bacillus cereus
None (intoxication)
27
Clostridium botulinum
Antiobiotics are contraindicated in infection; you will release more toxin into the body and make things worse
28
Clostridium perfringens
Penicillin + clindamycin or tetracycline
29
Clostridium tetani
Metronidazole
30
Corynebacterium diptheriae
Erythromycin or PenG
31
Gardnerella vaginalis
Metronidazole
32
Listeria monocytogenes (neonatal meningitis)
Ampicillin or PenG
33
Listeria monocytogenes (pregnancy)
Ampicillin
34
Listeria monocytogenes (gastroenteritis w/ fever)
Ampicillin or TMP-SMX
35
Mycobacterium avium complex
Clarithromycin or azithromycin
36
Nocardia
TMP-SMX
37
N. gonorrhea
Ceftriaxone + azithromycin for possible coexisting chlamydia
38
N. meningitidis
Ceftriaxone
39
Basically, if someone has listeria, your go to is...
Ampicillin
40
Moraxella cattharalis
Amoxicillin
41
Kleb pneumo
Cephalosporing +/- aminoglycoside
42
ETEC
Ciprofloxacin (if warranted)
43
EHEC
NONE; contraindicated, may release more toxin
44
HUS from EHEC
Eculizumab
45
EIEC
Fluoroquinolone (if warranted)
46
E. coli meningitis
3rd gen cephalosporin (ceftriaxone)
47
E. coli pneumonia
3rd-gen ceph or fluoroquinolone
48
E. coli UTI
Fluoroquinolone, TMP-SMX, nitrofurantoin
49
Salmonella (notyphoidal)
Fluoroquinolone
50
Salmonella (typhoidal)
Fluoroquinolone (adult), ceftriaxone (kid)
51
Pseudomonas (endocarditis, bacteremia)
Aminoglycoside +antipseudomonal b-lactam
52
What are the antipseudomonal beta-lactams
piperacillin, ticarcillin, ceftazidime, cefepime, imipenem)
53
Pseudomonas (meningitis)
Ceftazidime
54
Pseudomonas (Osteomyelitis)
Beta-lactam, carbapenem, fluoroquinolone
55
Pseudomonas (UTI)
Aminoglycoside or fluoroquinolone
56
Pseudomonas (pneumonia)
Antispeudomonal b-lactam, antipseudomonal quinolone+aminoglycoside
57
Vibrios
Fluid+electrolytes
58
Campylobacter
Fluoroquinolone or azithromycin
59
H. pylori
PPI+amoxicillin+clarithromycin
60
H. influenzae (otitis media)
Amoxicillin)
61
H. influenza (meningitis)
Ceftriaxone
62
Yersinia pestis
Streptomycin (gentamycin)
63
Bordatella pertussis
Macrolide (historically erythromycin)
64
Pasteurella multocida
Amoxicillin-clavulanate
65
Francisella tularensis
Streptomycin (or gentamycin)
66
Legionella
Levofloxacin (L for L)
67
Brucella
Doxy + streptomycin
68
Bacteroides
Metronidazle
69
HACEK (causing endocarditis)
Ceftriaxone
70
Mycoplasma pneumoniae
Macrolide or doxy
71
For all Chlamydia trachomatis infections, give what else besides the DOC
Ceftriaxone for possible coinfection with gonorrhea
72
Chlamydia trachomatis (NGU)
Azithromycin or doxycycline
73
Chlamydia trachomatis (neonatal conjuctivitis or pneumonia)
Erythromycin
74
Chlamydia trachomatis (LGV)
Doxycycline
75
Chlamydia trachomatis (Reactive arthritis)
NSAIDs
76
Chlamydophila pneumoniae
Macrolide if 8
77
Chlamydophila psittaci
Doxycycline
78
Treponema pallidum
Penicillin
79
Neurosyphillis
PenG
80
Leptospira
Doxy
81
Ricketsial diseases
Doxy for all (even in kids!)
82
Allergic aspergillosis
Corticosteroids
83
Aspergilloma (fungal ball)
Surgerize it
84
Systemic aspergilllosis
Voriconazole
85
Blastomyces dermatiditis
Amphoterecin B
86
Candida causing endocarditis, endopthalmitis
Amphotericin B (+flucytosine if endocarditis)
87
Candid causing esophageal candidiasis, oral candidiasis (AIDs pt), or peritonitis
Fluconazole
88
Oral candidiasis in non-AIDs pts
Nystatin
89
Candida causing pneumonia, septic arthritis, osteomyelitis, or UTI
Fluconazole OR ampho B
90
Vulvovaginal candidiasis
Topical azoles
91
Coccidiodes immitis (pulmonary)
Fluconazole
92
Coccidioides immitis (meningitis)
Ampho B for 4-6 weeks then azoles
93
Tinea capitis
Griseofulvin
94
Tinea pedis, corporis, cruris
Topical antifungal
95
Fusarium spp.
Topical natamycin
96
Histoplasma
Ampho B
97
Mucomycoses
Ampho B
98
Paracoccidiodes
Itraconazole
99
Pneumocytis jiroveci
TMP-SMX
100
Sporothrix schenckii (Rose gardener dx)
Itraconazole
101
Sporothrix schenckii (invasive)
Ampho B
102
Babesia microti
Clindamycin plus quinine
103
Cryptosporidium parvum
Nitazoxanide
104
Cyclospora cayetenensis
TMP-SMX
105
Entamoeba histolytic
Metronidazole
106
Giardia
Metro
107
Isospora
TMP-SMX
108
Microsporidia
Albendazole or umagillin
109
Naegleria fowleri
Amphotericin B + rifampin
110
Plasmodium falciparum (malaria)
Chloroquine
111
Plasmodium falciparum (cerebral malaria)
IV quinine
112
Plasmodium vivax
Chloroquine + primaquine
113
Toxoplasma gondii
Pyramethamine + sulfadiazine
114
Trichomonas
Metro
115
T. cruzi
Benznidazole
116
Ascaris lumbricoides (roundworm)
Albendazole
117
Enterobius vermicularis (pinworm)
Mebendazole
118
Loa loa (eye worm)
Diethylcarbamazine
119
Wucheria bancrofti (filiriasis)
Diethylcarbazine
120
Fasciola hepatica (Sheep liver fluke)
Bithionol
121
Shistosoma haematobium (hematuria)
Praziquantel
122
Shistosoma mansoni (bloody poo)
Prazi
123
Diphyllobothrium latum (fish tapeworm)
Niclosamide
124
Echinococus (hydatid cyst dx)
Al or mebendazole
125
Taenia saginata and taenia solium
Prazi
