Bronchodilators And Other Asthma Drugs Flashcards
LABA
Salmeterol, formeterol
IV-acute attack
Inhaler- controller
Arrythmic, may inc asthma mortality when used alone
SABA (b2 selective agonists)
Albuterol, salbutamol, terbutaline
Ipatropium, Tiotropium
Muscarinic receptor antagonist
SE: Dry mouth
Methylxanthine
PDE inhibition
Narrow therapeutic window
SE: seizure
Theophylline, aminophylline
Mast cell stabilizer
Cromolyn
*prophylaxis
SE: oropharyngeal candidiasis
Corticosteroids
Fluticasone, budesonide
*prophylaxis
Leukotriene synthesis inhibitor
No bronchodilator action
Zileuton
Leukotriene antagonists
No bronchodilator action
Montelukast, Zafirlukast
Omalizumab
Anti-IgE antibody
Prophylaxis
Cromolyn
Steroids
Zileuton
Antibody
Acute attack
SABA, IV corticosteroid, theophylline, muscarinic antagonists, leukotriene antagonists
Late response inflammation
Steroids, cromolyn, leukotriene antagonist