Agents Used In Anemias And Hematopoetic GF Flashcards

0
Q

SimD of ferrous sulfate administered through IV

A

Iron dextran, iron sucrose, sodium ferric gluconate complex

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1
Q

SimD of ferrous sulfate with high Fe content

A

Ferrous fumarate

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2
Q

Acute SE of Fe/chronic Fe overload

A

Necrotizing gastroenteritis / hemochromatosis

Antidote: deferoxamine

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3
Q

Role of B12 in RBC synth

A

Cofactor in transfer of 1-carbon unit in DNA synth

  • def cause neuro defects, not seen in folate deficiency
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4
Q

B12 absorbed in ___

A

Distal ileum

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5
Q

B12 deficiency

A

Tetrafolate is low

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6
Q

Neural tube defect

A

Folate deficiency

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7
Q

Absorption of frolic acid at

A

Proximal jejunum

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8
Q

Hematopoietic GF

A

Epoetin alpha

Hb level maintained below 12g/dl

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9
Q

DOC for neutropenia assoc with chemotx

A

Filgrastim, sargramostin (G-CSF)

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10
Q

Megakaryote GF

A

Oprelvekin (IL-11)

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