bronchodilators

Question 1

BETA 2

Answer 1

is where our sympathetic bronchodilators are active
-are imbedded in the smooth muscles lining the airways
are found from the trachea all the way to the distal bronchioles- they increase in number as you go down.
* most are not innervated by the sympathetic nerves

Question 2

Ventolin ( salbutamol sulphate)

Answer 2

Classification drug: SABA
MDI
fast onset (5mins)
duration : 4-6 hr
100mcg/dose

Question 3

Airomir (salbutamol sulphate)

Answer 3

MDI
SABA
100mcg/dose
duration: 4-6 h

Question 4

Bricanyl turbuhaler( terbutaline sulphate )

Answer 4

SABA
DPI
0.5mg/dose
duration: 4-6 h
*slightly older B2 may be used if salbutamol allergy is present. Slower onset to salbutamol

Question 5

Ventolin Diskus (salbutamol sulphate)

Answer 5

DPI
200mcg/ dose
duration; 4-6h

Question 6

What is a LABA

Answer 6

Long lasting Beta agonist
Maintenance/ preventative therapy
Use regularly- never used on its own * always with ICS when used to treat asthma

Question 7

Foradil Arolizer ( formoterol fumarate)

Answer 7

LABA - 12mcg/dose
duration 12 h

Question 8

Oxeze tubuhaler (formoterol fumarate)

Answer 8

DPI
6; 12 mcg/dose
duration: 12 h

Question 9

Severent Diskus (salmeterol xinafoate)

Answer 9

50mcg/ dose
DPI
duration 12 h

Question 10

what is a LAMA (asthma)

Answer 10

long acting muscarinic antagonist (blocks parasympathetic rx)
M3 mucarinic receptor
- never used on its own without an ICS

Question 11

Spiriva Respimat (Tiotropium bromide monohydrate)

Answer 11

2.5mcg/dose
Soft mist
duration; 24 hr

Question 12

Alvesco (ciclesonide )

Answer 12

MDI
ICS
100;200 mcg/dose
duration: 24 hrs

Question 13

Artuity Ellipta (fluticasone furoate)

Answer 13

ICS
100; 200 mcg dose
duration: 24 h
DPI

Question 14

Asmanex (thometasone furoate)

Answer 14

twishaler
100: 200: 400 mcg dose
duration: 24 h
ICS

Question 15

Flovent diskus and MDI (fluticasone propionate)

Answer 15

100; 500 mcg dose
duration: 12 h

Question 16

Pulmicort turbuhaler (budesonide)

Answer 16

100’ 200’ 400 mcg/ dose
duration: 12 h
ICS

Question 17

Qvar (beclomethasone dipropionate)

Answer 17

MDI
ICS
50: 100mcg dose
duration: 12 h

Question 18

name all ICS+ LABA Tx for Asthma

Answer 18

• Advair MDi (12h) 125/25’ 250/25 mcg/ dose
• Advair diskus )12h) 100/50; 250/50; 500/50 mcg/ dose
  -Breo (24h) (100/25; 200/25 mcg/dose)
  -Symbicort (12) (100/6; 200/6; 400/12 mcg) *onset less than 5 mins
  -Zenhale MDI (12h) (50/5; 100/5; 200/5 mcg doses)