anti histamine

Question 1

Anti- histamines

Answer 1

OTC/ hospitals
used in treatment of allergy reactions
multiple home and in hospital uses
Part of the Pharmacological treatment of Anaphylaxis
With Epinephrine and corticosteroids
Despite blocking Histamine receptors they have no current role in Asthma or COPD management

Question 2

H1 receptors

Answer 2

Are located throughout the body, with high concentrations in the CNS-brain stem, airway smooth muscle, vascular endothelial cells, mucosal glands, heart…

Question 3

anti histamines side effects

Answer 3

drowsiness / somnolence
from suppression on CNS
newer generations less likely to cross BBB
may also seen dry mouth, dizziness
may be potentiated by alcochol or sedative use

Question 4

diphenhydramine

Answer 4

Brand name : Benadryl
Older generation drug
Often seen in combination therapy OTC cold medications
Along with adrenergics, cough suppressants, and analgesics
Taken orally, either in liquid or pill form
Commonly used for allergic reactions at home or in the hospital

Question 5

newer generations

Answer 5

cause less CNS depression
loratidine (claritin)
brompheniramine (dimetapp)
decreased effects