Bronchiectasis * Flashcards

1
Q

What is Bronchiectasis

A

Permanent dilation of the bronchioles filled with mucus

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2
Q

What are the main presentations of bronchiectasis

A

Productive cough w/ sputum and dyspnoea

Signet ring sign (HRCT)

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3
Q

What are the RF for bronchiectasis

A

Post Infection
Cystic fibrosis
HIV
ABPA
Primary cilliary Dyskinesia
Whooping cough as child

CF/HIV Association

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4
Q

What is the pathology of Bronchiectasis

A

Irreversible dilation
Loss of cillia
Mucus hypersecretion
Increased risk of infection (lack of ciliary clearance)

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5
Q

What lobes are typically affected by bronchiectasis

A

Lower lobes

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6
Q

What are the investigations for bronchiectasis

A

Gold = HRCT = Dilated thick bronchi (“Signet sign) and tram tracks w/ bronchiole cysts
Spirometery = Obstructive (FEV1/FVC <0.7)
Sputum culture for infection
Bilateral inspiratory crepitations
Finger clubbing (Px w/CF)

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7
Q

What is the signet ring sign

A

Dilated thick bronchi on HRCT

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8
Q

Bronchiectasis is permanent so is not curative but how can it be managed

A

Chest physio and smoking cessation
Bronchiodilators
Abx for infection

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9
Q

What possible organisms can be found in the sputum culture of Bronchiectasis patient

A

Amoxicillin treated
-H Influenzae
-S Pneumoniae
and P auregunosa

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10
Q

What does spirometry of bronchiectases show

A

Obstruction
FEV1:FVC <0.7

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11
Q

What is the Gold investigation for Bronchiectasis

A

HRCT
-Signet ring (Dilated thick bronchi)
-Bronchiole terminal cysts

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12
Q

How does bronchiectasis increase the risk of infection

A

Reduced ciliary clearance
-More trapping of organisms

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13
Q

What can be heard on resp exam for bronchiectasis

A

Bilateral course cxrepitations

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14
Q

How eould you treat a bronchiectasis patient presenting w/ septic signs

A

IV Antibiotics

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15
Q

What is pathagnomonic sign of PCD

A

Sinus Invertus
-Shows left lung pain but pathology on right lung

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16
Q

How can P Auregunosa be managed

A

oral macrolide
Inhaled aminoglycaside

17
Q

Which oragnism commonly presents in bronchiectasis of a patient with CF (Finger clubbing)

A

P Auregunosa