Breast Pathology 1 Flashcards
IBFLAMMATORY BREAST DISEASE/ACUTE MASTITIS CAUSE, clinicals ? And microscopy
Bacteria(staph) gained access to breast tissue during lactation due to fissuring of nipples.
Clinical: redness, hotness, pain with multiple or single abscess
Micro: neutrophilic infiltration
Mammary duct ectasia(plasma cell mastitis) cause, clinicals, and microscopy ?
Non bacterial disease, due to dried up secretions on main excretory duct causing obstruction or rupture.
Clinically: peri aerolar mass, nipple RETRACTION.
Microscopy: lymphplasmacytic infiltration and lipid laden macrophages
Fat necrosis definition and microscopy
Hard and firm calcified lesions on the breast
Microscopy central focus of necrotic tissue, giant cells and laden macrophages
Fibrocystic disease of the breast incidence, gross and microscopy
Most common breast lesion during REPRODUCTIVE age, no advancing to breast carcinoma
Gross: multifocal bilateral nodular cysts
Microscopy: cystic spaces
Name me 3 Neoplastic lesions
Fibroadenoma, giant fibroadenoma (phyollodes tumor, intraduct papilloma)
Fibroadenoma clinical, micro and gross
Most common breast lesion
Clinical mobile mouse breast, discrete
Gross well defined and Grey
Micro both fibroblastic stroma and glands
Giant Fibroadenoma/ phyllodes tumor gross, microscopy, prognosis ?
Old age
Gross Leaflike projection
Micro glands and stroma but more stroma
Prognosis removed by excision and is localized
Intraductal papillary duct gross/ clinical and micro
Occurs often in PREMENOPAUSAL women
Gross/ clinical: serous blood discharge with sub areolar mass
Micro: multiple papillae
Intraductal papillary duct gross/ clinical and micro
Occurs often in PREMENOPAUSAL women
Gross/ clinical: serous blood discharge with sub areolar mass
Micro: multiple papillae
Klinefeller syndrome- liver cirrhosis- and anabolic steroids may cause ?
Gynecomastia
