Breast and peripheral vascular Flashcards

1
Q

Types of breast cancer

A

Non-invasive: can’t spread, can’t kill e.g. Paget’s (DCIS of nipple)

Invasive: can spread but treatable e.g. ductal (most common), lobular (second most common)

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2
Q

Breast cancer screening programme

A

Mammogram

50-70 every 3 years

Trial in some parts of England to do ages 47-73

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3
Q

Breast cancer investigations

A

Triple assessment
- History and physical exam
- Radiological exam (USS<35, MG>35)
- Histological exam (FNA)

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4
Q

Grading of breast cancer

A
  1. Normal
  2. Benign
  3. Indeterminate
  4. Suspicious
  5. Malignant
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5
Q

Breast cancer management

A

Chemotherapy
Surgery
Radiotherapy after surgery
ER +ve - hormone therapy
HER2 +ve - biological therapy

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6
Q

When would you do excision vs mastectomy

A

Excision - solitary, small in large breast, DCIS <4cm

Mastectomy - multifocal, large in small breast, DCIS >4cm

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7
Q

Lactational mastitis management

A

Continue breastfeeding
Analgesia
Flucloxacillin

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8
Q

Non-lactional mastitis management

A

Broad-spectrum abx e.g. co-amoxiclav

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9
Q

Breat abscess management

A

USS guided aspiration

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10
Q

When should you use incision and drainage in breast abscess?

A

If pus is really thick, but need to explain risk of fistula formation

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11
Q

When do you excise a fibroadenoma?

A

> 3cm

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12
Q

ABPI interpretation

A

1.0-1.2 - normal
0.8-0.9 - mild claudication
0.5-0.79 - severe claudication
<0.5 - critical limb ischaemia

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13
Q

Investigation for intermitten claudication

A
  1. Duplex USS
  2. ABPI
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14
Q

Intermittent claudication management

A

Conservative - stop smoking, supervised exercise training, treat HTN/DM/obesity
Medical - clopidogrel, statin

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15
Q

Difference between critical limb ischaemia and acute-limb threatening ischaemia

A

Acute has sudden pain (<2 weeks) rather than gradual pain at rest
Acute may be pale, pulseless, paralysed, paraesthetic, or cold

Critical has gangrene and ulcers

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16
Q

Investigations for critical limb ischaemia and acute-limb threatening ischaemia

A

Bedside: Duplex USS (first), ABPI
Bloods: lactate, thrombophilia, G&S
Imaging: MR angiography

17
Q

How is ABPI calculated

A

Highest of dorsalis pedis or posterior tibial artery pressure / brachial pressure

18
Q

Critical limb ischaemia management

A

Conservative
Medical - clopidogrel, statin
Surgical - angioplasty, stenting, amputation

19
Q

When is amputation done in limb ischaemia?

A

Rutherford class III:
Loss of sensation
Severe motor impairment
Absent arterial and venous doppler signals

20
Q

Acute limb ischaemia management

A

A-E
IV opioids
IV heparin

Vascular review for surgical embolectomy, angioplasty etc.

21
Q

Most common peripheral vascular bypass

A

Femoral-popliteal