Breast Flashcards
Galactography
radiopaque dye injected into ductal opening on the areola
ultrasonography
helps to diagnose cysts, but not to r/o malignant lesions
MRI
highly sensitive
Breast biopsy
- fine needle aspiration
- ultrasound guided
- Stereotactic: x-ray guided, lies prone, breast suspended (core needle)
- MRI guided: similar to stereotactic and used for lesions not visualized with mammography
- surgical
Excisional
removes entire lesion and surrounding margin-Lumpectomy
Incisiona;
a portion of the mass removed
Breast pain
mastalgia
Breast Cysts
common nonproliferative breast lesions
- not a breast cancer risk
- fluid filled over ovoid masses
- Simple: may require aspiration
- Complex: fluid and solid; requires core biopsoy r/o malignancy
- Fibrocystic breast changes
Fibroadenomas
proliferative lesions without atypia (cell abnormalities)
Benign Proliferative Breast Disease
- atypical hyperplasia
- Lobular carcinoma in Situ
Atypical Hyperplasia
- abnormal increase in the ductal cells or lobular cells
- pre-malignant
- increases chance of breast cancer
- multiple lesions and may be associated with microcalcifications
Lobular Carcinoma in Situ
- Proliferation of cells within the breast lobules
- Not seen on mammography and not palpable lump
- Marker for increased risk for invasive carcinoma (8-10)
- active surveillance
What is the inherited genetic mutation
BRCA1 and BRCA2
Symptoms of breast cancer?
- upper outer quadrant
- nontender, fixed and hard with irregular borders
- advanced signs: skin dimpling, nipple retraction, or skin ulceration
What to look at for prognosis
tumor size, axillary lymph node involvement, tumor type