Breast Flashcards

1
Q

Symmetric shrinking breast?

A

Invasive lobular breast CA

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2
Q

Breast MR is best performed during which days of the menstrual cycle?

A

days 6-12 (less background enhancement)

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3
Q

What is the difference between multifocal and multicentric breast cancer?

A

Same quadrant versus different quadrant.

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4
Q

At the time of biopsy, DCIS will have what % chance of having invasive component?

A

10%

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5
Q

At the time of surgical excision, DCIS will have what % chance of invasive component?

A

25%

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6
Q

How often will DCIS present as a mass without calcs?

A

8/100

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7
Q

Most common cause of bloody discharge?

A

intraductal papilloma.

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8
Q

Malignant degeneration risk of phyllodes?

A

10% (some texts 25%)

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9
Q

What lifetime risk qualifies for screening MRI?

A

20-25%, 20Gy rad to chest as a kid

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10
Q

During which menstrual cycle phase is parenchymal enhancement the worst?

A

Luteal- days 14-28

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11
Q

What is the required resolution of the line pairs in mammography?

A

13 lp/mm in anode/cat direction and 11 in R to L

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12
Q

Target range for medical audit: recall rate

A

5-7%

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13
Q

Target range for medical audit: cancers/1000 screened

A

3-8

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14
Q

Which cyst features are LEAST likely to show posterior acoustic enhancement?

A

small and deep

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15
Q

Which type of calcifications “tend to coalesce”?

A

Coarse heterogenous.

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16
Q

The proliferative phase of the menstrual cycle includes which days?

A

days 3-14, aka “follicular phase”

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17
Q

Screening MRI for high risk patients is not recommended until atleast what age?

A

25

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18
Q

Alternate name for hamartoma?

A

Fibroadenolipoma

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19
Q

What do the BRCA 1/2 genes do?

A

DNA damage response/repair

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20
Q

What is the strongest risk factor for developing breast cancer?

A

patient age

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21
Q

What percent chance is there that an intraductal papilloma gets upgraded?

A

15-20%

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22
Q

What is the study of choice when seaching for primary CA with breast origin?

A

MR

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23
Q

Anatomically, where do most breast cancers start?

A

TDLU

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24
Q

60% of blood flow to breast is from___?

A

internal mammary

remaining is lateral thoracic and intercostal perforators

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25
breast lymph drains to \_\_\_\_?
97% to axilla and 3% to internal mammary
26
What are the axillary lymph node levels?
1. Lateral to pec minor 2. under pec minor 3. medial to pec minor 4. between pec major and minor
27
if you see interanl mammary node on u/s...
cancer
28
Where is the sternalis seen?
ONLY CC view, never MLO next to sternum
29
MC location for ectopic breast tissue?
axilla
30
2nd MC place for ectopic breast tissue?
inframmary fold
31
When is the best time to have mammo and MRI?
Follicular phase day 7-14 estrogren dominates
32
in what phase is breast density increased?
luteal day 15-30 progesterone
33
Nipple enhancement on MRI.
normal (not Pagets)
34
in what quadrant do most cancers occur?
upper outer
35
breast tenderness maxes out at day\_\_\_?
27-30
36
Risk assoc with Bx during lactaion?
milk fistula
37
benign fat containing lesion after lactation
galactocele fat fluid level
38
looks like fibroadenoma, but patient is lactating
lactating adenoma next step: f/u 4-6 mos post-partum with ultrasound, regress after lactation
39
What is the margin of error with posterior nipple lines in MLO and CC views?
1 cm
40
What view do you get sometimes in women with kyphosis or pectus excavatum?
LMO view also can be used to avoid a medial pacemaker or cental line
41
which standard view contains the most breast tissue?
MLO
42
what are the standard mag views?
cc and ML views (milk of Ca2+)
43
If cooper ligaments are thick or fuzzy, what artifact are we dealing with?
blur 2/2 motion or inadequate compression. could also be edema- look for skin thickening
44
When is a grid not used?
mag views
45
how many breast cancers are you trying to find per 1k mams?
3-8
46
explain: "lead sinks muffins rise"
lesion that is medial on the CC film will be superior on the MLO and even more superior on ML Lesion that is lateral will become more inferior
47
What does BIRADS stand for?
Breast Imaging-Reportand and Data System
48
What is BI-RADS 0?
needs further workup or technical repeat
49
BI-RADS 1
normal
50
BI-RADS 2
Benign. cysts, secretory calcs, fat containing lesions "mult bilat well circ similar appearing masses" "mult foci"
51
BI-RADS 3
less than 2% chance cancer fibroadenoma focal asymmetry that becomes less dense on compression (breast tissue) grouped or clustered round calcifications
52
BI-RADS 4
2-95% chance malignancy going to bx it (regardless of 4A, 4B, 4C) prepare for B9 result
53
BI-RADS 5
\>95% chance CA if path comes back B9, recommend surg bx
54
BI-RADS 6
path proven cancer
55
Definition of "mass" on mammo?
spcae occupying lesion seen in 2 projections
56
vocab to describe a mass?
1. Shape: round, oval, irregular **ROI** 2. margin: circ, obscured, microlobulated, indistict, spiculated **COMIS** 3. density: fat, hypo, iso, hyperdense \*margin is most important
57
What is the definition of "asymmetry" on mammo?
unilateral deposition of tissue that doesn't quite look like a mass seen in 1 view * global* asymmetry is volume asymmetry * focal* seen in two projections, needs spot comp, might be a mass * developing* is new or growing
58
How to describe a mass on ultrasound.
1. Shape: round, oval, irregular 2. orientation: parallel, antiparallel 3. margin: circ, indistinct, angular, microlobulated, spiculated 4. echo pattern: anechoic, hyperechoic, hypoechoic, isoechoic, complex 5. posterior features: none, enhancement, shadowing
59
Descriptors for masses on MRI
irregular: shape and margin oval circumscribed T2 signal
60
descriptors for non-mass like enhancement on MRI
linear and linear branches clustered ring T2 signal
61
Earliest mammo finding of breast cancer according to some
calcs
62
high density material in the axilla
deodorant
63
What is the most suspicious calc distribution? least?
segmental-\> linear -\> grouped/clustered -\> regional -\> scattered
64
what view is good for confirming dermal calcs?
tangential view
65
fancy name for hamartoma?
fibroadenolipoma
66
what is the risk of sclerosis adenosis transforming to carcinoma?
~2% if there is ADH- risk is closer to 7% biopsy is recommended