Breast

Question 1

Causes of gynaecomastia

Answer 1

The P’s

Physiological
- neonates
- purbety
- older age

Pathological
- testicular cancer
- breast cancer
- liver failure

Pharmacological
- spirololactone
- androgen blockers (eg finaterade)

Obesity - pseudogynaecomastia

Question 2

Subtypes of DCIS

Answer 2

Comedo
Cruciform
Micropapillary
Papillary
Solid

Question 3

Genetic conditions breast cancer

Answer 3

bRCA 1
BRCA 2
pALB2

CHEK2
sTK11 (peutz jeugher)
PTEN (cowdens)
CDH1
ATM
Li Fraunmeni

Question 4

When should you re-excise for a positive LCIS margin?

Answer 4

Pleomorphic LCIS

Question 5

Breast biopsy classification

Answer 5

B1 - normal breast tissue
B2 - benign (not cancer)
B3 - abnormal or uncertain but probably benign
B4 - suspicious and possibly cancer
B5 - cancer