bph, CA, acute kidney injury Flashcards
bph
increased testosterone = increased number of cells inner part of gland
BPH obstructive symptoms
urinary retention, weak stream, difficulty initiating, intermittency, dribbling
BPH irritative symptoms
Increased frequency, urgency, dysuria, bladder pain, nocturia, incontinence
BPH comps
UTI from incomplete bladder emptying, Calculi in bladder from alkalinization from urine, Hydronephrosis and pyelonephritis bc of urine backpressure
BPH dx
DRE, PSA>4= transrectal US
BPH treatment
5a reductase inhibitor[-ide] pregnant women shouldnt handle, a-adrenergic receptor blocker [-osin]-htn meds to increase relaxation to decrease symptoms=retrograde ejaculation (w TURP too) saw palmetto helps urinary symptoms, ^BP/Bleeding
Prostate cancer
androgen dependent
Prostate cancer mets s/s
pain lumbosacral area->hips/legs
Prostate CA dx
DRE , PSA>4, biopsy
Prostate CA treatments
radical prostatectomy(!), radiation beam if confined, Brachytherapy (time, distance, shielding), cryosurgery freezes
Prostate CA meds
Lh+FSH to decrease testosterone=gynecomastia, hot flash, , androgen receptor blocker
Testicular CA mets s/s
chest pain, cough, dyspnea
cryopreservation to save sperm
Acute Kidney injury caused by
renal ischemia- disruption of basement membrane nephrotoxic injury (acute tubular necrosis)- tubules get clogged
Acute kidney injury characterized by
rapid loss of kidney function (^cr, decrease UO, ^BUN-azotemia)
Acute kidney injury follows what
lots of hypotension, hypovolemia, nephrotoxic agents
Acute kidney injury Oliguric phase
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