Bot Med - Urinary Tract Flashcards
What is a urinary tract infection?
typically a bacterial infection of the the bladder (e.g. cystitis ) or kidneys
(e.g. pylonephritis)
Symptoms of UTI?
- dysuria (painful urination)
- urgency
- turbid (cloudy) urine
- hematuria (bloody urine)
Herbal actions useful for treating UTI?
- diuretic
- urinary antiseptic
- antiadherence
- demulcent
- astringent
Herbs useful for treating UTI; Antiadherance? Antiseptic? Demulcents? Astringents?
Antiadherance • cranberry juice (Vaccinium spp.) • blueberies (Vaccinium spp.) Antiseptic • bearberry (Arctostaphylos uva-ursi) • juniper (Juniperus communis) Demulcents • marshmallow (Althaea officinalis) Astringent • horsetail (Equisetum arvense)
Cautions regarding UTIs?
Bladder infections that spread to the kidneys (pylonephritis) are a serious
medical condition and must be managed aggressively.
Diuretic (aquaretic) does?
Increases the production and elimination of urine.
When would one use a diuretic?
- urinary tract infections (UTI)
- kidney stones
- detoxification
Herbs with diuretic properties?
- parsley (Petroselinum crispum)
- juniper (Juniperus communis)
- bear berry (Arctostaphylos uva-ursi)
Phytochemicals in diuretics?
- essential oil
* alkaloids (e.g. methylxanthines)
Actions of parsley (petroselinum sativum)?
- diuretic
- carminative
- antispasmodic
when would one use parsley?
• urinary tract infections (UTI)
Phytochemicals in parsley?
- phenylpropanoids (apiole, myristicin)
- furanocoumarin (psoralen, bergapten)
- flavonoids
What does parsely inhibit in the kidneys, leading to what?
Parsley inhibits the Na+/K+-ATPase pump in the kidney leading to
sodium and water excretion and potassium reabsorption.
Cautions regarding parsley?
• Pregnancy (uterine stimulant) - myristicin is an abortifacient in high
doses
•Side effects: Photosensitization may occur due to furanocoumarins.
Urinary antiseptics do?
discourages or inhibits the growth of microorganisms in the urinary tract.
when would one use urinary antiseptics?
urinary tract infections (UTI)
what herbs have urinary antiseptic properties?
- juniper (Juniperus communis)
* bear berry (Arctostaphylos uva-ursi)
phytochemicals on urinary antiseptics?
- essential oil
* alkaloids (e.g. methylxanthines)
Actions of bearberry (Arctostaphylos uva-ursi)?
- antiseptic (urinary)
* astringent
when would one use bearberry?
urinary tract infections
phytochemicals of bearberry?
- arbutin (hydroquinone glycoside)
* tannins
how does hydroquinone of arbutin become active?
Beta-glucosidase enzyme cleaves the sugar from arbutin releases the
active hydroquinone.
Caution regarding bearberry?
arbutin generates reactive oxygen species and thus long-term use may
increase the risk for cancer.
Juniper (Juniperus communis) actions?
- diuretic
- urinary antiseptic
- antimicrobial
When would one use Juniper?
urinary tract infections
phytochemicals on Juniper?
- volatile oils (monoterpene & sesquiterpenes)
* monoterpenes (α-pinene, myrcene, camphor, terpinen-4-ol)