Bordetella Flashcards
Bordetella causes kennel cough and ____ in swine
atrophic rhinitis
Bordetella are aerobic bacteria that infect the ______ of hosts
ciliated respiratory epithelium
Which Bordetella species have flagella?
Bordetella bronchiseptica and B. avium
True/False: Bordetella is highly variable
True
difficult for vaccination
Which species of Bordetella causes porcine atrophic rhinitis and Canine kennel cough?
Bordetella Bronchiseptica
*can lead to bronchopneumonia in many species
What species of Bordetella causes Turkey Coryza?
Bordetella Avium
What virulence factor does Bordetella express, but only in warm environments of around 37 degrees?
BvgAS- bordetella virulence gene
*avirulent at 25 degrees
What kind of disease is associated with Bordetella?
respiratory
Bordetella can cause _____
hemagglutination
What important virulence factor of Bordetella helps with adherence to the respiratory tract?
Tracheal colonization factor
*This is only expressed by Bordetella Pertussis. Targets trachea. Not expressed in Bordetella Parapertussis or Bronchiseptica
What outer membrane proteins does Bordetella have?
Pertactin and Brk (Bordetella resistance to killing)
What siderphore is particular to Bordetella species?
Alcaligin
What type of secretion system does Bordetella use?
Type III secretion system
What are the 5 exotoxins important with Bordetella and what do they do?
Tracheal cytotoxin- toxic to cells within the trachea
Dermonecrotic toxin- destruction of turbinates in atrophic rhinitis
Adenylyl cyclase toxin- results in fluid loss
Pertussis Toxin- only active in B. pertussis and results in fluid loss
Osteotoxin- lethal to tracheal and bone cells
How is Bordetella transmitted?
Direct Contact
*needs close contact