Bordetella

Question 1

Bordetella causes kennel cough and ____ in swine

Answer 1

atrophic rhinitis

Question 2

Bordetella are aerobic bacteria that infect the ______ of hosts

Answer 2

ciliated respiratory epithelium

Question 3

Which Bordetella species have flagella?

Answer 3

Bordetella bronchiseptica and B. avium

Question 4

True/False: Bordetella is highly variable

Answer 4

True

difficult for vaccination

Question 5

Which species of Bordetella causes porcine atrophic rhinitis and Canine kennel cough?

Answer 5

Bordetella Bronchiseptica

*can lead to bronchopneumonia in many species

Question 6

What species of Bordetella causes Turkey Coryza?

Answer 6

Bordetella Avium

Question 7

What virulence factor does Bordetella express, but only in warm environments of around 37 degrees?

Answer 7

BvgAS- bordetella virulence gene

*avirulent at 25 degrees

Question 8

What kind of disease is associated with Bordetella?

Answer 8

respiratory

Question 9

Bordetella can cause _____

Answer 9

hemagglutination

Question 10

What important virulence factor of Bordetella helps with adherence to the respiratory tract?

Answer 10

Tracheal colonization factor

*This is only expressed by Bordetella Pertussis. Targets trachea. Not expressed in Bordetella Parapertussis or Bronchiseptica

Question 11

What outer membrane proteins does Bordetella have?

Answer 11

Pertactin and Brk (Bordetella resistance to killing)

Question 12

What siderphore is particular to Bordetella species?

Answer 12

Alcaligin

Question 13

What type of secretion system does Bordetella use?

Answer 13

Type III secretion system

Question 14

What are the 5 exotoxins important with Bordetella and what do they do?

Answer 14

Tracheal cytotoxin- toxic to cells within the trachea

Dermonecrotic toxin- destruction of turbinates in atrophic rhinitis

Adenylyl cyclase toxin- results in fluid loss

Pertussis Toxin- only active in B. pertussis and results in fluid loss

Osteotoxin- lethal to tracheal and bone cells

Question 15

How is Bordetella transmitted?

Answer 15

Direct Contact

*needs close contact

Question 16

Bordetella leads to depression of respiratory _____ and can lead to secondary ____ complications

Answer 16

depression of respiratory clearance

secondary pneumonia complications

Question 17

In pigs, nasal irritation associated with Bordetella can open the doors for _____ to infect

Answer 17

Pastuerella Multocida

Question 18

What is the medical term for kennel cough?

Answer 18

Canine infectious tracheobronchitis

Question 19

What other pathogens can co-infect with Kennel cough?

Answer 19

parainfluenza virus

adenovirus

canine herpesvirus

Question 20

Dogs with ____ are at a higher risk for develping pneumonia associated with Bordetella because they are immunosuppressed

Answer 20

distemper

Question 21

True/False: Coughing is common in cats with Kennel cough?

Answer 21

False

*couging is not common with cats

Question 22

Atrophic rhinitis is associated with what two bacteria?

Answer 22

Bordetella Bronchiseptica and Pasteurella Multocida

Note on image: KNOW THESE IMAGES. B and C show pig after infection when there has been erosion of nasal turbinates

Question 23

Atrophic rhinitis usually occurs in ____ pigs and _____ are carries that can spread the bacteria to their progeny and other progeny

Answer 23

occurs in young pigs

Sows are carriers

Question 24

True/False: Turkey Corya is highly infectious and causes high mortality

Answer 24

False

it is highly contagious in young turkeys but has a low mortility rate of less than 5%

Question 25

What does Turkey Coryza cause in the trachea?

Answer 25

tracheal degenration and flattening making it hard for the bird to breath

Question 26

If Bordetella comes into the mix with Snuffles (P. multocida) then it can cause _____ in rabbits

Answer 26

Bronchopneumonia

Question 27

Bordetella depresses the immune system by telling ____ cells not to secrete as much

Answer 27

dendritic cells

Question 28

Bordetella are strict \_\_\_\_

Answer 28

aerobes \*they are in the respiratory tract

Question 29

What is the best way to control Atrophic Rhinitis?

Answer 29

vaccines are available for pigs CLEAN facility \*not treatable in advanced cases

Question 30

What is the best way to control Canine tracheobronchitis?

Answer 30

ventilation of kennels to keep the air moving \*vaccination doesn't help much

Question 31

Is there a vaccine available for Turkey Coryza?

Answer 31

Yes