Book 4- Cell membrane and Transport Flashcards
Cell membranes have a what structure? why?
fluid mosaic because the phospholipids are constantly moving from side to side.
What does cholesterol do in the cell membrane?
makes it less acidic
What do phospholipids consist of?
A phosphate head which Is hydrophilic, so is positioned outside of the membrane towards water. Two fatty acid tails, which are hydrophobic, meaning they are positioned in-between the phosphate heads away from water.
What is the function of the phospholipid bilayer? (3)
- ) allow lipid soluble substances to enter and leave the cell
- ) prevent water soluble substances from entering and leaving a cell
- ) make the membrane flexible
4 functions of the cell membrane?
- ) Transport- molecules cross the membrane via transport proteins or between phospholipids
- ) Digestion- contain enzymes which can hydrolyse molecules
- ) Immune response- cell membranes contain specific glycoproteins( antigens). they contain specific protein receptors which can bind to foreign antigens and cause an immune response.
- ) cell signalling- hormones can bind to receptor proteins causing a signal to be sent to trigger a response.
Molecules can cross the phospholipid bilayer if they are what?? (3)
- ) small
- ) lipid soluble-dissolve in fats
- ) Non-polar- so the polar phosphate heads are unaffected
Types of transport?
diffusion, facilitated diffusion, active transport, co-transport, osmosis
Explain simple diffusion
the net movement of particles from a high conc to a low conc. This does not involve membrane protein and doesn’t require energy. Small, lipid soluble molecules can diffuse through a bilayer.
What does facilitated diffusion allow?
Allows the transport of polar molecules across membranes using channel and carrier proteins.
Explain facilitated diffusion?
- protein spans the membrane
- ions such as Na+ pass through the protein pore
- a glucose molecule diffuses into carrier protein molecule
- the glucose molecule binds with the carrier protein causing it to change shape.
- the glucose molecule diffuses out of the carrier protein molecule
What is active transport?
the movement of molecules or ions through a partially permeable membrane by carrier proteins against a conc gradient. It requires ATP
Explain how active transport occurs?
- ATP hydrolase breaks down ATP, releasing energy required for active transport.
- the energy is used to attach the molecule to the carrier protein and to provide energy for the carrier to change shape to move the ion through the membrane
- cells involved possess a lot of mitochondria to provide the ATP via respiration
factors which decreases the rate of respiration, therefore will decreases active transport are??
- ) lowering of temp
- ) lack of oxygen
- ) metabolic and respiratory inhibitors eg.cyanide
give 2 examples of co transport?
sodium-potassium and sodium-glucose proteins
Factors affecting transport?
conc gradient, diffusion distance, molecule size, temperature, number of channel/carrier proteins, surface area