Bone Tissue & Microscopic Structure Flashcards
How are bones living?
Bones are living tissues. Bones contain cells as well as a calcified extracellur matrix.
Why do bones change?
Depending on how you are using your body. Bone cells respond to external forces. Bones also repair themselves.
How much of bone ECM is organic, and what is the organic products
33%
Collagen and Ground substances
What is collagen function and what will happen to the bone without collagen?
Resist tension- respond by making bone flexible.
Without collagen bone will be very brittle.
How much of ECM in bone is inorganic and what is the organic components?
67% Mineral salts (hydroxyapatite + other Ca minerals.
What happens without inorganic components in the bone?
The mineral component makes bones hard and resistant too compression. If we take out the inorganic components this creates the bone to become too flexible.
What makes up 2% of bone matrix
The cellular component of bone
What are the four different types of cells?
osteogenic cells Osteoblasts Osteocytes Osteoclast Together these cells maintain bone homeostasis.
What does each cell do?
osteogenic cells- stem cells that produce osteoblasts
Osteoblasts- Produce new bone matrix
Osteocytes- Recycle protein and minerals from matrix
Osteoclast- Remove bone matrix
What are the structures of compact and cancellous bone?
compact= osteon structure
Cancellous- trabecular structure. Marrow that fills cavities between trabeculae.
What is osteons? (osteon)
Longitudinal unit with compact bone.
It provide pathway for nutrients to get to cells in the ECM.
What is the central canal (osteon)
Contains blood vesels and nerves.
What is lamellae (osteon)
A series of cylinders formed of ECM around the central canal.
Forms shape of osteons
Collagen fibres within lamellae resist forces.
What is lacunae (osteon)
Lakes for osteocytes
What is canaliculi (osteon)
Channels for nutrients through ECM
