bone tissue & its microscopic structure (lecture 4)

Question 1

describe the extracellular matrix components of bone structure

Answer 1

33% of bone ECM is organic which gives our bones flexibility & resists tension
67% of bone ECM is inorganic which gives the rigid structure & resists compression
these two work together to ensure a balance required for function and weight bearing

Question 2

what processes allow for bones to maintain the bodies homeostasis

Answer 2

maintaining our bone structure and ensuring the nutrients from the bone matrix can be released and used to its full potential through bone remodelling, as well as balanced OB & OC activity.

Question 3

what is a common result of lack of homeostasis in bone pathology

Answer 3

osteoporosis, is a condition that occurs when osteoblastic activity does not keep up (by building bone tissue) with the rate at which osteoclastic activity is (catashrophising and killing bone tissue cells), as a result the loss of cortical bone reduces the bones strength and can result in compression fractures due to thin structure

Question 4

Name the four types of cells present in the cellular component of bone

Answer 4

Osteogenic cells (stem cells produce osteoblasts)
Osteoblasts (build)
Osteocytes (maintain)
Osteoclasts (kill)

Question 5

explain compact bones microscopical make up

Answer 5

made up of circumferential lamellae and osteon units, osteons provide pathways for nutrients to get to cells in ECM

Question 6

Describe bone tissues composition

Answer 6

contains connective tissue, and its inorganic and organic extracellular components