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MMD1042: Module 1 > Bone Tissue 1: > Flashcards

Bone Tissue 1: Flashcards

1
Q

Where does tissu hématopoïétique reside?

A

Inside the bones
This is the Red blood and White blood cell progenitors

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2
Q

What are the two components of the extracellular bone matrix?

A

La matrice organique (ostéoïde):

Fibres collagènes + Substance fondamentale

Mainly Type I collagen

La matrice minérale:

65% of all the MEC

Complexe d’ions et de sels minéraux: Calcium and Phosphate

This is what makes bone hard!!!

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3
Q

Which part of the ECM makes bone hard and what proportion does this take?

A

La matrice minérale:

65% of all the MEC

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4
Q

What are the main components of the La matrice minérale?

A

Complexe d’ions et de sels minéraux: Calcium and Phosphate

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5
Q

What is the main content of La matrice organique ?

A

Fibre collagen type I

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6
Q

What are the 5 cells of bone tissue?

A

ostéogéniques
osteoblaste
osteocytes
cellules bordantes
osteoclaste

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7
Q

What are the only bone cells capable of diving?

A

cellules ostéogeniques

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8
Q

Wher edo you find cellules ostéogeniques in bone?

A

dans la couche interne du périoste
de l’endoste
sur les parois des canaux de Havers

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9
Q

What are perioste and endoste?

A

Kinda like perichondre for cartilage
they line the outside and iside of bone

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10
Q

True or False, Osteoblasts will divide to give osteocytes.

A

FALSE.
Osteoblasts are cellules différenciées qui ne se divisent plus

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11
Q

What cell is responsible for the secretion of ECM in bone?

A

Osteoblasts

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12
Q

What cell is responsible for the mineralization of bone?

A

Osteoblasts

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13
Q

What are cellules bordante and what is their main role?

A

At rest Osteoblasts
Ne se divisent pas

Ostéoblastes en repos, elles reprennent leur activité au besoin

Protection contre la dégradation de la MEC, régulation du Ca++ et de la nutrition de l’os

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14
Q

How are osteocytes formed?

A

Osteoblasts release bone material, imprison themselves becoming osteocytes

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15
Q

What are vésicules matricielles?

A

Released by ostéoblastes
contiennent beaucoup de
calcium et une variété
d’enzymes qui génèrent le
phosphate, ce qui va aboutir
à formation des foyers de
minéralisation

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16
Q

What is the role of osteocytes?

A

Renouvellement et maintenance de la MEC

Remodelage osseux (en sécrétant de
l’acide citrique, de la phosphatase acide,
des enzymes protéolytiques et des
peptidases).

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17
Q

What is Lacune de Howship?

A

Formed by the bone breaking process of ostéoclastes

18
Q

True or False, Osteoclasts travel from blood vessels and have a singular nuclei.

A

FALSE

19
Q

How do osteoclasts break bone?

A

Starts by breaking mineral tissue:
Through acidification

Phagocytic activity

Bone reabsorption

20
Q

What are the two possible bone morphology stuctures?

A

Couche externe rigide, l’os compact (os cortical):

Os spongieux (os trabéculaire):

Structure important to lower bone weight.

Includes moelle hématopoïétique → Bone marrow.

Can also find moelle osseuse jaune → Adipose tissue.

With age moelle osseuse jaune is increased.

21
Q

What is moelle osseuse jaune?

A

Adipose tissue inside the Os spongieux.

With age moelle osseuse jaune is increased.

22
Q

What are the three possible bone morphology based on shape?

A

Os long
Os Court
Ost Plat

23
Q

What are the parts of os long and their properties?

A

Diaphyse :
contains the cavité médullaire in the inside
composed of compact bone on the outside

Épiphyse:
Made of os spongieux in the center
Limited between the diaphyse by the cartilage de conjugaison fill later
Does not have os compact on the outside but rather cartilage articulaire

Metaphyse

24
Q

What is metaphyse?

A

It is the Zone de la croissance de l’os: Métaphyses

25
Q

What bone does this describe:
Os spongieux + 2 couches d’os compact revêtues par un périoste

A

Os plat

26
Q

What bone does this describe: Os spongieux entouré d’un os compact

A

Os court

27
Q

What covers the outside of compact bone?

A

le périoste

28
Q

What are Sharpey fibers?

A

Le périoste est solidement
attaché à l’os grâce à des
faisceaux de collagène qui
s’enfoncent dans les lamelles
circonférentielles externes de l’os
appelés: les fibres de Sharpey.

29
Q

What is Le tissu osseux non-lamellaire?

A

primary; non-mature bone; only present in fetus
Collagen Fibers are not oriented on the same direction.

30
Q

True of False, Le tissu osseux lamellaire is found only in compact bone tissue

A

False.
Can be compact ou spongieux

31
Q

True of False, Le tissu osseux non-lamellaire is found only in compact bone tissue

A

False.
Can be compact ou spongieux

32
Q

What is the difference between Le tissu osseux non and -lamellaire in terms of Ostéocytes?

A

Ostéocytes régulièrement répartis entre les
lamelles

33
Q

What are the three types of Lamellar Bone?

A

L’os lamellaire compact Haversien
L’os lamellaire compact non-Haversien
L’os lamellaire spongieux ou trabeculaire

34
Q

What do we find in the canal de havers?

A

Canal de Havers: capillaires sanguins + fibres nerveuses
And on the around we have osteoblasts

35
Q

What connects two canal de havers?

A

canal de Volkman.

36
Q

What do we find between the lamelle of an osteon?

A

ostéocytes

37
Q

What is the role of L’os lamellaire compact non-Haversien?

A

It is the Le système circonférentiel → The connection of système Havers to périoste and endoste.

It is what separates l’os Haversien de l’endoste et du périoste

38
Q

What is Système interstitiel?

A

Because the bone is in continuous breakage and rebuild, we find between osteons this system of incomplete osteons:

Système interstitiel

39
Q

TRUE OR FALSE, we can find os haveresien (osteons) in both spongeous and compact bone/

A

FALSE.

Osteons only in compact bone

You can find L’os lamellaire spongieux ou trabéculaire in spongeous bone

40
Q

Where do we find L’os lamellaire spongieux ou trabéculaire?

A

L’os du diploë des os plats, les os courts, les
épiphyses et les métaphyses des os longs

The spongieus bone

41
Q

How can spongious bone be lamellare?

A

Les lamelles de l’os spongieux ne sont pas circulaires, mais plutôt parallèles à la surface des travées

MMD1042: Module 1 (21 decks)

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