Bone development (osteogenesis)

Question 1

Intermembranous ossification

Answer 1

fetal into childhood, many skull bones /facial, plus clavicle. This is good for giving birth . Starts in the mesenchyme and center of bone and moves superficially

Question 2

Endochondral ossification

Answer 2

Begins at fetal and ends when full height is reached
Bone tissue replaces cartilage

Question 3

Primary ossification (shaft)

Answer 3

Uses center to out and out to in
Chondrocytes calcify the matrix
bone collar formed
cells migrate to medullary cavity to form spongy bone

Question 4

Secondary ossification (ends)

Answer 4

Chondrocytes calcify
Blasts invade and create spongy bone
Hyaline remains at outer layer of epiphysis

Question 5

Bone remodeling

Answer 5

Occurs at the periosteal and endosteal surface
It is a constant process but depends on the function and use of the bone

Question 6

Osteoblasts

Answer 6

Lay down matrix

Question 7

Osteoclasts

Answer 7

Break down matrix
Ca2+ released into blood