Bone and Soft Tissue Tumours Flashcards

1
Q

What is a sarcoma?

A

A malignant tumour of connective tissue

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2
Q

How can sarcoma spread?

A

Fascial planes
Haematogeous spread to lungs
Rarely to regional lymph nodes

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3
Q

Is it more common for a bone primary tumour to be benign or malignant?

A

Benign

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4
Q

How are malignancies of bone likely to come about in over 50s?

A

Metastatic spread

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5
Q

What are examples of benign bone tumours?

A

Osteoid osteoma, osteoblastoma

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6
Q

What are examples of benign cartilage tumours?

A

Enchondroma

Osteochondroma

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7
Q

What is a malignant bone tumour called?

A

Osteosarcoma

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8
Q

What a malignant cartilage tumour called?

A

Chondrosarcoma

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9
Q

What is a benign fibrous tissue tumour called?

A

Fibroma

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10
Q

What are examples of malignant fibrous tissue tumours?

A

Fibrosarcoma

Malignant fibrous histiocytoma

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11
Q

What are examples of benign vascular tissue tumours?

A

Haemangioma

Aneurysmal bone cyst

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12
Q

What is a malignant vascular tissue tumour called?

A

Angiosarcoma

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13
Q

What is a benign adipose tissue tumour called?

A

Lipoma

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14
Q

What is a malignant adipose tissue tumour called?

A

Liposarcoma

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15
Q

What are examples of malignant marrow tissue tumours?

A

Ewing’s sarcoma
Lymphoma
Myeloma

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16
Q

What is the main symptom of a primary bone symptom?

A

PAIN

17
Q

What are features of pain in bone tumours?

A

Activity related

Progressive pain at rest and at night

18
Q

What should be done when examining a tumour?

A
General health of patient
Measurement of mass
Location of tumour
Shape of tumour
Consistency
Mobility
Tenderness
Local temperature
Neuro-vascular deficits
19
Q

What investigations can be done for tumours?

A

X-rays
Calcifications
Myositis ossificans
Phleboliths in haemangioma

20
Q

What is isotope bone scan used for?

A

Staging for skeletal metastasis

21
Q

What are multiple lesions on an isotope bone scan a sign of?

A

Osteochondroma
Enchondroma
Fibrous dysplasia
Histiocytosis

22
Q

What is MRI specific for?

A

Lipoma
Haemangioma
Haematoma
Pigmented VilloNodular Synovitis

23
Q

What are cardinal features of malignant primary bone tumours?

A
Increasing pain
Unexplained pain
Deep-seated boring nature
Night pain
Difficulty weight bearing
Deep swelling
24
Q

What are clinical features of osteosarcoma?

A
Pain
Loss of function
Swelling
Pathological fracture
Joint effusion
Deformity
Neurovascular effects
Systemic effects of neoplasia
25
Q

What loss of function is a result of osteosarcoma?

A

Limp
Reduced joint movement
Stiff back

26
Q

How is Ewing’s sarcoma treated?

A

Chemotherapy
Surgery
Radiotherapy

27
Q

What should you do with patient’s with a suspected malignant soft tissue tumour?

A

Refer to specialist tumour centre

28
Q

What are signs that would make you suspicious of a soft tissue tumour being malignant?

A
Deep to fascia
Subctuaneous tumours >5cm
Rapid growth
Hard
Craggy
Non-tender
29
Q

7 commonest primary cancers metastasising to bone?

A
Lung
Breast
Prostate
Kidney
Thyroid
GI tract
Melanoma
30
Q

What scoring system is used to assess fracture risk assessment?

A

Mirel’s scoring system

31
Q

How is the site scored in Mirel’s scoring system?

A

Upper limb - 1
Lower limb - 2
Peritrochanter - 3

32
Q

How is pain scored in Mirel’s scoring system?

A

Mild - 1
Moderate - 2
Functional - 3

33
Q

How is lesion scored in Mirel’s scoring system?

A

Blastic - 1
Mixed - 2
Lytic - 3

34
Q

What is scored in Mirel’s scoring system?

A

Site
Pain
Lesion
Size

35
Q

What score in Mirel’s scoring system is indicative of prophylactic fixation before radiotherapy?

A

8 or more