Bone Flashcards

1
Q

osteocyte

A

mature bone cells

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2
Q

osteoblast

A

makes bone

they are a deposit matrix

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3
Q

osteoclast

A

breaks down bone (and then the body reabsorbs the calcium)

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4
Q

yellow bone marrow

A

function is to store fat

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5
Q

red bone marrow

A

function is to produce blood cells

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6
Q

osteoperosis

A

when breakdown of bone exceeds deposition
bones loose density, become weak and fragile
importance of calcium, vitamin D, and exercise

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7
Q

thyroid hormone (TH)

A

necessary in bone growth

regulates metabolic rate and stimulates protein synthesis

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8
Q

growth hormone (GH)

A

primary function is to stimulate growth–> stimulates bone growth

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9
Q

vitamin D

A

promotes absorption of calcium

sources: dairy, eggs, “fatty” fish, meat, sunglight

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10
Q

calcitonin

A

decreases plasma concentration of calcium

moves calcium from plasma to bone

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11
Q

parathyroid hormone (PTH)

A

increases plasma concentration of calcium
moves calcium from bone to blood
decreases loss of calcium in urine

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12
Q

functions of bone

A
  • support
  • movement
  • protection
  • storage of materials (bone is major calcium reservoir)
  • storage of fat (yellow bone marrow)
  • produces blood cells (red bone marrow)
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13
Q

What do the development of bone in the fetus and the repair of a broken bone have in common?

A

repair of broken bone begins by the bone producing cartilage. the skeleton of a fetus is made of cartilage
cartilage cells divide and make more cartilage which allows the fetus’s skeleton to grown and a broken bone to heal

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14
Q

What hormones are involved in bone growth?

A

thyroid hormone
growth hormone
sex hormones

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15
Q

What hormones are involved in the cessation of the elongation of bones when a child reaches puberty?

A

sex steroids promote bone elongation until puberty, then inhibit bone elongation

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16
Q

Where is growth hormone produced?

A

in the anterior pituitary

17
Q

What is the consequence of too little growth hormone?

A

pituitary dwarfism

18
Q

What is the consequence of too much growth hormone?

A

gigantism

19
Q

What hormones are involved in regulating plasma-calcium concentration?

A
  • PTH (parathyroid hormone)
  • calcitonin
  • vitamin D
20
Q

Why is tight regulation of the plasma concentration of calcium critical? (calcium homeostasis)

A

Calcium is important for:

  • signaling
  • cell to cell connections
  • blood clotting
  • neuronal excitability
21
Q

What is the role of vitamin D and how does it affect bone health?

A

role: promotes absorption of calcium

affects bone health by keeping bones strong, fights osteoporosis