Bone Flashcards

1
Q

What is the impact of Estrogen on bone modelling?

A

It inhibits osteoclast resorption and periosteal formation

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2
Q

As we age, what happens to our bone in terms of the size?

A

The size increase via periosteal bone formation
But we lose endocardial bone via resorption

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3
Q

What cell can become an osteocyte

A

Osteoblasts

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4
Q

Osteoclasts take how long to eat away at bone?

A

3-4 weeks

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5
Q

Full osteoid mineralisation takes how long?

A

About a year

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6
Q

Over what timeframe does activation of osteoclasts occur?

A

10 days

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7
Q

A bones ability to resist mechanical load comes down to what three factors ?

A
  1. Quantity - mass and density
  2. Organisation - architecture
  3. Quality - mineral, micro damage, collagen
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8
Q

What are the 6 risk factors for RED-S

A
  1. BMD <1
  2. 12 hours or more of exercise a week
  3. BMI <21
  4. Oligo-amenorrhea
  5. Elevated dietary restraint
  6. Participation in “leanness” required sports
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9
Q

What was found to be an effective CMJ dosage program for improving bone density

A

20 jumps, 3 times a day and 3 times a week

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10
Q

What is the most common BSI region in basketball ?

A

MT

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11
Q

Three most common regions for BSI in long distance running ?

A

Tib/Fib

MT

Femur

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12
Q

Name 5 high risk BSI regions?

A
  1. Femoral neck
  2. Anterior tibial cortex
  3. Navicular
  4. Base of 2nd MT
  5. Proximal shaft of 5th MT
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13
Q

What is the first stage of imaging algorithm in a suspected BSI?

A

X-ray - if negative and not suspected at a high risk site, then crack on

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14
Q

What is the T vs Z score?

A

T = BMD compared to 30 year old healthy sex matched

Z = BMD COMPARED TO AGE AND sex matched individual

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15
Q

At what point does someone have OP

A

-2.5 points below where the should be

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16
Q

What does QCT stand for

A

Quantitative computer tomography

17
Q

With bone loading, is volume or intensity more important ?

A

Intensity

18
Q

Uphill and up stairs compared to flat, what’s the difference for born stress

A

Uphill is much less force through the bone

19
Q

What loads the bone more, overground or treadmill running?

A

Overground

20
Q

What loads the bone more, stair climber or treadmill?

A

Treadmill

21
Q

What three factors reduce when increasing cadence ?

A
  1. Step length
  2. Vertical excursion
  3. Braking force
22
Q

How does increasing cadence reduce braking forces

A

Leads to less overstriding, which results in a more vertical tibia = less eccentric loading through tibia

23
Q

What is the leading hypothesis for how osteocytes sense mechanical load ?

A

Compression side of the bone cause fluid to flow to the tension side

24
Q

What two exercise factors need to be high to induce adaption to bone cells?

A

Magnitude - think resistance training

Rate - think ploys

25
Q

What’s the optimal dosage for bone loading programs

A

Bone goes deaf after around 20-30 loading cycles

26
Q

Over what period of time do bones resensitise and therefore are able to be loaded again ?

A

4 hrs restores 75%

8 hrs restores 85%

27
Q

When can you only develop bone size?

A

When young

28
Q

When does periosteal absorption occur?

A

It never does. Your bone loses endocortical mass (from the inside) as you age

29
Q

How well does bone size last through the life span if you’d played sport younger?

A

Size and strength generally remains throughout the life span, mass does not

30
Q

Exercising during growth enhances what bone qualities ?

A

Mass and size

31
Q

After developing a robust skeleton from adolescence, what qualities can remain into older age?

A

Size and strength