Boncher Exam 1 Flashcards

1
Q

penicillin binding protein AKA

A

transpeptidase

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2
Q

penicillins come from

A

6-aminopenicillanic acid

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3
Q

natural penicllins

A

Pen G and Pen V

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4
Q

natural penicllin spectrum

A

Gram + cocci
Gram + bacilli
Gram - cocci (not bacilli)
Spirochetes

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5
Q

Anti-Staphylococcal Penicillins

A

Naficillin, Oxacillin, Dicloxacillin, Cloxacillin

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6
Q

Anti-Staphylococcoal spectrum

A

Staph, not MRSA

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7
Q

Pen G route

A

parenteral

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8
Q

Pen V route

A

oral

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9
Q

to target MRSA

A

vancomycin

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10
Q

aminopenicillins

A

“smart penicillins”

ampicillin and amoxacillin

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11
Q

aminopenicillin spectrum

A

streptococci and enterococci

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12
Q

aminopenicillin AE

A

diarrhea

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13
Q

amoxacillin brand

A

Amoxil

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14
Q

amoxacillin + clavulanate

A

Augmentin

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15
Q

ampicillin brand

A

Ampi, Omnipen

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16
Q

ampicillin + sulbactam

A

Unasyn

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17
Q

green pus means

A

pseudomonas infection

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18
Q

anti-pseudomonals

A

piperacillin, ticarcillin, azlocillin, mezlocillin, carbenacillin

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19
Q

piperacillin brand

A

Pipracil

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20
Q

piperacillin + tazobactam

A

Zosyn

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21
Q

Ticarcillin + clavulanic acid

A

Timentin

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22
Q

anti-pseudomonal spectrum

A

pseudomonas, streptococci, enterococci, enteric Gram -

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23
Q

cycloserine MOA

A

prevent addition of terminal D-Ala, D-Ala

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24
Q

vancomycin MOA

A

inhibit enzyme for glycosylation

25
Q

bacitracin MOA

A

inhibit BPP

26
Q

bactericidal drugs

A

penicillins, cephalosporins, aminoglycosides, vancomycin, fluoroquinolones, metronidazole

27
Q

ampicillin absorption

28
Q

amoxicillin absorption

29
Q

cephalosporins based on

A

7-aminocephalosporanic acid (7-ACA)

30
Q

cephalosporin MOA

A

inhibit PBP

31
Q

cephalosporins don’t cover

A

enterococci, C. diff, Listeria

32
Q

cefadroxil brand and generation

A

Duricef, 1st gen

33
Q

cephalexin brand and generation

A

Keflex, 1st gen

34
Q

Cefazolin brand and generation

A

Kefzol, 1st gen

35
Q

cefaclor brand and generation

A

Ceclor, 2nd gen

36
Q

cefprozil brand and generation

A

Cefzil, 2nd gen

37
Q

cefuroxime brand and generation

A

Ceftin, 2nd gen

38
Q

cefoxitin generation

39
Q

cefdinir brand and generation

A

Omnicef, 3rd gen

40
Q

cefixime brand and generation

A

Suprax, 3rd gen

41
Q

cefditoren brand and generation

A

Spectracef, 3rd gen

42
Q

ceftibuten brand and generation

A

Cedax, 3rd gen

43
Q

cefpodoxime brand and generation

A

Vantin, 3rd gen

44
Q

ceftriaxone brand and generation

A

Rocephin, 3rd gen

45
Q

cefotaxime brand and generation

A

Claforen, 3rd gen

46
Q

Ceftazadime brand and generation

A

Fortax, 3rd gen

47
Q

cefepime brand and generation

A

Maxipime, 4th gen

48
Q

ceftaroline brand and generation

A

Teflare, 5th gen

49
Q

monobactams

50
Q

aztreonam brand

51
Q

aztreonam spectrum

A

narrow, mostly gram -

52
Q

carbapenems

A

irtapenem/cilastatin, meropenem, ertapenem, doripenem

53
Q

carbapenem spectrum

A

broad, gram + and gram -, not MRSA

54
Q

carbapenem route

A

parenteral

55
Q

imipenem + cilastatin

56
Q

meropenem brand

57
Q

ertapenem brand

58
Q

doripenem brand

59
Q

major carbapenem AE