body fluid compartments Flashcards

1
Q

describe the blood supply through the kidneys

A
  1. renal artery
  2. interlobar artery
  3. arcuate artery
  4. interlobular artery
  5. afferent artery
  6. efferent artery
  7. interlobular vein
  8. arcuate vein
  9. interlobar vein
  10. renal vein
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2
Q

what happens to the efferent arteriole after it leaves the renal corpuscle

A

outer renal corpuscle = efferent artery –> interlobular vein –> arcuate vein –> interlobar vein –> renal vein
OR
deep renal corpuscle = drains into venous vasa recta

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3
Q

define osmolality

A

number of osmotically active particles per unit weight of solvent
- determines the osmotic pressure exerted by a solution across a membrane

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4
Q

define osmolarity

A

number of osmotically active particles per litre of total solution

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5
Q

define tonicity

A

the osmotic pressure a solute exerts across a cell membrane

- accounts only for osmotically active impermeable solutes rather than osmotically active

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6
Q

how do cells balance the oncotic pressure across their membranes and prevent cells from bursting?

A

pump out osmotically active ions (Na+) via Na/K/ATPase transporter
K+ and proteins inside balance Na+ outside

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7
Q

what are the effects of a high sodium diet

A
  • increase in plasma osmolality
  • increased renal salt excretion
  • increased thirst (water retained to maintain ECF osmo)
  • plasma osmo returns to normal but at expense of larger ECF volume (higher BP0
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8
Q

what regulates and controls osmolality

A
  • regulated tightly by renal water handling

- controlled by ADH

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9
Q

what regulates and controls ECF volume

A
  • regulated by renal Na+ handling

- controlled by renin-angiotensin system & SNS

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