body fluid compartments Flashcards
describe the blood supply through the kidneys
- renal artery
- interlobar artery
- arcuate artery
- interlobular artery
- afferent artery
- efferent artery
- interlobular vein
- arcuate vein
- interlobar vein
- renal vein
what happens to the efferent arteriole after it leaves the renal corpuscle
outer renal corpuscle = efferent artery –> interlobular vein –> arcuate vein –> interlobar vein –> renal vein
OR
deep renal corpuscle = drains into venous vasa recta
define osmolality
number of osmotically active particles per unit weight of solvent
- determines the osmotic pressure exerted by a solution across a membrane
define osmolarity
number of osmotically active particles per litre of total solution
define tonicity
the osmotic pressure a solute exerts across a cell membrane
- accounts only for osmotically active impermeable solutes rather than osmotically active
how do cells balance the oncotic pressure across their membranes and prevent cells from bursting?
pump out osmotically active ions (Na+) via Na/K/ATPase transporter
K+ and proteins inside balance Na+ outside
what are the effects of a high sodium diet
- increase in plasma osmolality
- increased renal salt excretion
- increased thirst (water retained to maintain ECF osmo)
- plasma osmo returns to normal but at expense of larger ECF volume (higher BP0
what regulates and controls osmolality
- regulated tightly by renal water handling
- controlled by ADH
what regulates and controls ECF volume
- regulated by renal Na+ handling
- controlled by renin-angiotensin system & SNS