BODY FLUID Flashcards
Water constitutes ______ of total body weight
60%
Typical 154-lb or 70kg lean adult male: _____or ____kg of body weight is water
93 lbs or 42
Decreases with aging: body water decreases to ______ of TBW
45%
Intracellular fluid constitutes _____ of person’s body weight or ____
40%, 28L
The 2 primary cations in the ICF (positively charged)
Potassium & magnesium
How many percent of potassium can be found in ICF? In ECF?
98%, 2%
2 Principal anions in ICF (negatively charged)
Phosphates (PO3)
Sulphates (S04)
2 Solutes in ICF
Glucose
Oxygen
Extracellular fluids accounts for approximately _____
of the total body weight or about _____
20% or 14L
What is the function of ECF?
Transport nutrients to and out of cell
ECF contains high concentrations of ________, _________, and _________
Sodium, chloride and bicarbonate
2 primary cations in the ECF
Sodium chloride
Bicarbonate
Bicarbonate act as a________ and it is excreted by the _________
Buffer system, kidneys
Normal value of bicarbonate is?
22 - 26 mEq/L
What are the 3 classification of ECF
Interstitial fluid
Intravascular fluid
Transcellular fluid
Classification of ÉCF that is located in spaces between most of the cells
Interstitial fluid
Interstitial fluid accounts for approximately _______ of total body weight
15%
Classification of ECF that is contained within the arteries, capillaries and veins
Intravascular fluid
Intravascular fluid accounts for approximately_______ of TBW
5%
Classification of ECF that contains urine, digestive secretions, perspiration, cerebrospinal, pleural, synovial, intraocular, gonodal and pericardial fluids
Transcellular fluid
Produced by hypothalamus but stored and released by pituitary gland, increases water reabsorption
Antidiuretic hormone (ADH)
How does RAAS activated
Causes juxtaglomerular cells → Renin→Angiotensinogen (released by liver) → Angiotensin I → Angiotensin II (potent
vasoconstrictor) → stimulate adrenal glands →aldosterone (pro sodium, anti-potassium) → Na and H2O reabsorption→ ↑Circulating Blood Volume
Responds to increased circulating blood volume and it inhibits RAAS
Atrial natriuretic peptide (ANP)
How does thirst mechanism activates
Excessive perspiration → increased SO → send signal to hypothalamus → activate thirst mechanism → polydipsia
↑ADH → H2O reabsorption → ↓Urine output → ↓ SO
It is the the numberof solutes in the blood
Serum osmolality
Normal values of serum osmolalilty
270 - 290 mOsm/kg H2O
Hormones that releases by the posterior pituitary gland
ADH & oxytocin
Normal values of sodium
135 - 145 mEq/l