Blood vessels, pressure and regulation Flashcards
What determines systemic circulation?
Anatomy of the circulatory system
Hemodynamis of blood flow
Regulatory mechanisms
What are the functions of peripheral circulation?
Carry blood Exchange nutrients, waste products, gases Transport important substances Regulate blood pressure Direct blood flow
What lines the entire cardiovascular system?
Endothelium
Simple squamous epithelium
What is laminar flow?
Streamlined flow when the interior of the blood vessel is smooth
What is turbulent flow?
Interrupted flow caused by constriction, sharp turns, rough surfaces
What is blood flow?
The volume that passes a specific point per unit time
What determines flow rate?
The pressure differenced between two points
What is resistance?
How difficult it is for blood to flow between two points at any given pressure difference
What is poiseuille’s law?
Flow decreases when resistance increases and vice versa
What is viscosity?
Measure of resistance of liquid to flow
What is hematocrit?
Percentage of red blood cells per total blood volume
Where does resistance of blood flow occur?
In the arterioles
Where is pressure held constant?
Larger arteries
What is compliance
How stretchy the vessel is
Why does blood pressure increase with age?
Because of the decrease in compliance of the vessels
What are the two ways to control vasoconstriction/dilation?
Local controls
Extrinsic or reflex controls
What are the 4 local controls?
Active hyperemia
Flow autoregulation
Reactive hyperemia
Local response to injury
What are the 3 extrinsic controls?
Sympathetic nerves
Noncholinergic/nonadrenergic autonomic nerves
hormones
What is active hyperemia?
Increased blood flow to the tisssues due to increased metabolic rate
What is flow autoregulation?
If arterial pressure is reduced in an organ, arteriolar dilation will return flow back to normal
What is reactive hyperemia?
When blood flow is blocked to a tissue, there is a profound transient increase in its flow
What is the local response to injury?
Secretions during inflammatory response result in vasodilation to increase blood flow to the damaged tissue
What do alpha 1 receptors cause?
Vasoconstriction
What does sympathetic nerve stimulation cause?
Vasoconstriction
Do parasympathetic nerves influence arterioles?
No
What do noncholinergic/nonadrenergic autonomic neurons release?
Nitric oxide
What does nitric oxide cause?
Vasodilation
Where are noncholinergic/nonadrenergic neurons found?
In the digestive organs
What do beta 2 receptors cause?
Vasodilation