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Pathology > Blood Transfusion And Blood Groups > Flashcards

Blood Transfusion And Blood Groups Flashcards

1
Q

Blood collecting bag called as

A

CHITRA BAG

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2
Q

Ratio of blood volume and Anticoagulant solution

A

50:7 ratio
Example - 350ml Blood + 49ml Anticoagulant solution

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3
Q

Anticoagulant solutions

A

ACD - Acid citrate dextrose
CPD - Citrate phosphate dextrose
CPD-A - Citrate phosphate dextrose - Adenine
SAGM - Saline adenine glucose mannitol, Citrate/phosphate

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4
Q

Shelf life of blood

A

ACD - 21 Days
CPD - 21 Days
CPD-A - 35 Days
SAGM - 42 days - preferred chemical

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5
Q

Whole blood shelf life

A

Depends on added anticoagulant
Maximum 42 Days when added with SAGM

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6
Q

Whole blood stored at what temperature

A

2-6°C

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7
Q

Packed RBC Shelf life and storing temperature

A

21-49 days
Temp. 2-6°C

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8
Q

Platelets shelf life

A

5 days

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9
Q

Platelets stored at temp.

A

20-24°C

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10
Q

Fresh frozen plasma shelf life and temperature

A

1 year
-18°C

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11
Q

Cryoprecipitate shelf life and storing temperature

A

1 year
-18°C

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12
Q

Cryoprecipitate contains

A

vWF, Factor Viii, Xiii and Fibrinogen

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13
Q

Fresh frozen plasma contains

A

All clotting factors except vWF, factor 8,13 and Fibrinogen

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14
Q

Whole blood transfusion needs in case of

A

Massive blood transfusion
Exchange blood transfusion

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15
Q

Packed RBC transfusion in case of

A

Severe anemia
Prevents fluid overload

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16
Q

Platelet transfusion in case of

A

Thrombocytopenia

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17
Q

Fresh frozen plasma in case of

A

Burns - if fluid loss
Clotting factors deficiency

18
Q

Cryoprecipitate transfusion in case of

A

In deficiency of vWF, CF 8, 13 and Fibrinogen

19
Q

Which component of whole blood is not necessary to be ABO Compatible

A

Cryoprecipitate

20
Q

Blood transfusion set consists of

A

Transfusion needle - 18-19gauge
Micropore filter - 170-200micron

21
Q

Whole blood transfusion should be started within after taking out from blood bank

A

Within 30 minutes and finish within 4 hours

22
Q

Fresh frozen plasma and Cryoprecipitate should be transfused within

A

ASAP and should be finished within 20 minutes

23
Q

Complications during blood transfusion in donor

A

Bruise or hematoma on injection site
Vasovagal syncope
Local site complications
Hypocalcemia (due to citrate) - Perioral numbness and tingling sensation

24
Q

How to prevent donor complications during blood transfusion

A

Slow infusion
Oral calcium

25
Q

Complications in recipients during transfusion

A

Fever
Acute hemolytic transfusion reaction
Allergic reactions
TRALI
Post transfusion purpura
GVHD
Infections

26
Q

Fever in receipents during blood transfusion can be due to

A

Febrile non hemolytic transfusion reaction (FNHTR)
Most common Blood transfusion reaction

27
Q

Fever in receipents during blood transfusion can be due to

A

Febrile non hemolytic transfusion reaction (FNHTR)
Most common Blood transfusion reaction

28
Q

Acute Hemolytic transfusion reaction also known as

A

Mismatch blood transfusion

29
Q

Mismatching is mostly due to

A

Clerical error

30
Q

Clinical symptoms in mismatching

A

Fever +++
Abdominal/flank pain
Hemoglobinuria

31
Q

Management of Mismatching blood transfusion

A

Stop blood transfusion immediately
Iv acess + - Give normal saline
Send blood sample of patient and blood bag to check once again

32
Q

Sign of Mismatching blood transfusion in anesthetic or unconscious patient

A

Oozing from venipuncture site
Fever

33
Q

Most common allergic reaction during blood transfusion

A

Anaphylaxis - Type 1 HR
High risk in IgA deficiency patient

34
Q

TRALI Full form

A

Transfusion associated acute lung injury

35
Q

TRALI Happens

A

Within 6 hours after giving Fresh frozen plasma

36
Q

TRALI Pathogenesis

A

It happens when donor antibodies agglutinates with recipients antibodies - these WBCs goes to lungs - increases lungs permeability - can lead to Non cardiogenic pulmonary edema

37
Q

Post transfusion purpura is seen in case of

A

Platelets transfusion
Usually seen after 7-10 days

38
Q

GVHD Full form

A

Graft versus host disease

39
Q

GVHD usually seen in

A

Immunocompetent donor T cells
Within 8-10 days

40
Q

Infections are seen most commonly in

A

Platelet transfusion

41
Q

Massive blood transfusion means

A

If blood volume (5L) given within 24 hours
Or
More than 50% of blood volume given within 3 hours

42
Q

Complications of Massive blood transfusion

A

1) Hypothermia
2)Electrolyte disturbances - Hyperkalemia , Hypocalcemia and Metabolic alkalosis
3) Dilutional coagulopathy

Pathology (14 decks)

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