blood & tissue protozoa Flashcards

Y2C1 1 question will be asked

1
Q

malaria caused by_____

which is a plasmodium ssp.

A

protozoan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Human malaria transmitted via______mosquito

this mosquito has over 60 species

A

Anopheles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Female anopheles mosquito is____host

A

definitive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

_____pattern occcurs in area over a period of several years

A

endemic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

** periodic or occasional sharp rises occur in its incidence

A

epidemic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

life cycle of plasmodium vivax

1st step is injection of____by mosquito during blood meal

transportation and repliacton occurs on human

A

sporozoites

plasmodium vivax’s 1st form

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

life cycle of plasmodium vivax

2nd step
sporozoites infects____cells

A

liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

life cycle of plasmodium vivax

after sporozoites infects liver cells new formation occurs called ?

3rd step

A

schizont

1st appearence in cycle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

life cycle of plasmodium vivax

ruptured schiozont merozoites liberated and invade ?

4th step

A

RBC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

life cycle of plasmodium vivax

after invasion of schiozont merozoites early____forms

A

trophozoite

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

maturation of trophozoite & schizont formation occurs at ?

trophosite matures and forms schizonts

A

RBC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

life cycle of plasmodium vivax

how mosquito gets infected ?

A

ingests gametocytes via blood meal

gametocytes forms spozoites after undergoing meiosis inside of mosquito

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

clinical features of malaria

no symptoms during**stage

incubation period 1-6 weeks

A

liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

cliniacl features of malaria

characterized by acute___attacks

also known as malarial paroxysms

A

febrile

periodic episodes of fever alternating with sypmtom-free periods

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

clinical features of malaria

symptoms of malaria ?

7 exists

A

malaise
fatigue
fever
myalgia
arthralgia
dry cough
anorexia

fever can be up to 40.6 celsius

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

malarial paroxysm

prodrome 2-3 days before
* can mistake for_____or______infection
* slight_____may worsen just prior to pasoxysm

A

influenza and gastrointestinal infection
slight fever

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

malarial paroxysm

symptoms that seen in prodrome ?

6 exists

A

malaise
fever
fatigue
muscle pains
nausea
anorexia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

malarial paroxysm

how long paroxysm lasts in hours ?

A

8-12 hours

starts between midnignt and midday

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

malarial paroxysm

____stage characterized by rigors

starts in paroxysm stage

A

cold stage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

malarial paroxysm

____stage max temp can reach 40-41 celsius spelnomegaly easily palpable

palpable=visible
spelnomegaly=enlarged spleen

A

hot stage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

malarial paroxysm

sweating stage occurs at_____

A

hot stage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

diagnosis of malaria

thick microscopic films used for ?

A

presence/absence of malaria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

diagnosis of malaria

thin microscopic films used for ?

A

morphology/species

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

malaria microscopy

which type malaria is this

A

P. falciparum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
# malaria microscopy which type malaria is this
p.vivax
26
# malaria microscopy which type malaria is this
p. malariae
27
# malaria microscopy which type malaria is this
P. ovale
28
# Malaria in pregnancy malaria has high risks both maternal & perinatal____and____
morbidity & mortality
29
# malaria in pregnancy severe malaria should be treated aggressively with________therapy
antimalarial
30
# babesiosis babesiosis are______parasites
intraerythrocytic sporozoan
31
# babesiosis morphologically resemble_____
plasmodium
32
# babesiosis cause________like ilness in animals
tick borne like
33
# babesiosis _______infections in humans(intermediate host)
opportunistic
34
# babesiosis definitive host is______
Ixodid ticks
35
# babesiosis 3 impo species exists which are
B. microti(rodents) B. clivergens(cattles) B. bovis(cattles)
36
# life cycle of babesiosis parasites trophozoites merozoite formation occurs in which animal(s) ? ## Footnote check babesiosis life cycle pic if ur blue
mouse
37
# life cycle of babesiosis parasites sexual formation of sporozoites known as sporogony occurs at which animal ?
tick
38
# Babesiosis how long is incubation period for babesiosis ?
1-4 weeks following tick bite 1-9 weeks after contaminated blood transfusion
39
# Babesiosis:clinical features there is no______like paroxysm babesia infection can range from_____to_______ mild____&____ ______anemia ______ ______
malaria-like mild chills and fever hemolytic anemia jaundice hepatomegaly
40
# babesiosis:risk factors _____and impaired______function advanced age
asplenia impaired immune function
41
# babesiosis no of parasites per RBC ?
1-12 | 1-3 for malaria
42
# Babesiosis:laboratory diagnosis ID of intraerthrocytic babesia parasites by ?
peripheral blood smear examination under light microscope PCR IFA testing total Ig
43
# Toxoplasmosis etiologic agent____is most populations are____ threat to______&_____ Infected women can pass______to fetus via bloodstream domestic____and felines are main reservoirs
T. gondii seropositive immunosuppressed and unborn women cats
44
# toxoplasmosis:Transmission Ingestion of______& toxoplasma____ ____from fecally contaminated hands or food _____transplantation or____transfusion ________transmission accidental inoculation of ______
uncooked meat & toxoplasma cyst oocyst organ transplantation or blood transfusion transplacental transmission tachyzoites
45
# toxoplasmosis:symptoms ___is mostly fatal
prenatal
46
# babesiosis:preventation and treatment people w/ healthy immune systems no____needed risk groups should avoid___&___contact | cogenital toxoplasmosis oral pyrimethamine w/ folinic acid ## Footnote Immunocompromised patients trimethoprim-sulfmethoxazole dapsone-pyrimethamine
treatment Cat&feces contact
47
# Leishmaniasis transmitted by____flies new world:_____ old world:____ parasites replicate within____
sand flies lutzomyia phlebotomus macrophage | macrophage is vertebrate host's
48
# leishmaniasis: cutaneous leishmaniasis:causes lesions on____(CL) mucocutaneous:skin lesions spred over____(MCL) viseral leishmaniasis:infection of________system, high____(kala-azar)
skin mucosa reticuloendothelial mortality
49
# leishmaniasis:life cycle which ones are the diagnostic stages ?
3,4
50
# leishmaniasis:life cycle promastigotes phagocytized by macrophages and transform into____ | DİAGNOSTİC STAGE!!!
amastigotes
51
# leishmaniasis:life cycle after amastigotes formed they multiply in cells and_____ | DİAGNOSTİC STAGE!!!
infect other cells
52
# trypanosomiasis:african domain causes_____sickness 3 species causes this vector:___flies
sleeping disease T. brucei rhodesiense T.brucei gambiense tse tse
53
# trypanosomiasis:american domain causes___disease vector: parasite:
changa's disease T.cruzi reduviids-kissing bugs
54
# trypanosomiasis:african domain travel or residence in___area irregular___and enlarged____ _____changes, mental symptoms
endemic fever & lymph node behavioral changes
55
# trypanosomiasis:african domain lab diagnosis _____tests
serological
56
# american trypanosomiasis transmission _____bugs _____transmission ______route treated with_____or______ | parasite in feces of bug
kissing bugs blood transmission transplesental route benznidazole or nifurtimox
57
# american trypanosomiasis:acute phase mostly_____ active infection
asymptomatic | children most likely to be asymptomatic
58
# american trypanosomiasis:Interdeterminate phase ___years of latency seropositive with no detectable______
10-30 parasitemia
59
# american trypanosomiasis:chronic phase 10-30% of infected exhibit______and conduction defects congestive____failure _____phenomenon
cardiomyopathy arrhythmias congestive heart failure thromboembolic
60
fill the blanks
T.rhodesiense T.gambiense epidemiology:sporadic, sarafis endemic some epidemics disease progression:rapid,, often fatal slow paresitemia:high low asymptomatic carriers:rare common