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Forensic Biology > Blood Lecture 3 > Flashcards

Blood Lecture 3 Flashcards

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1
Q

Antibody =

A

Alpha

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2
Q

Alpha H =

A

Antihuman serum

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3
Q

Serum

A

Clear yellowish fluid obtained when whole blood is separated into its solid and liquid components

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4
Q

Immunology

A

An antihuman serum is produced by injecting human serum into an animal of another species, such as rabbit, horse, or bird

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5
Q

Antihuman sera react most strongly with what protein?

A

Human albumin (most abundant protein)

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6
Q

Antigens

A

Any molecule or pathogen capable of eliciting an immune response

  • antigens impart blood types to RBC’S
  • more then 15 blood type systems
    • ABO & RH most important
  • stimulates antibody generation
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7
Q

O - no antigens
A - A antigen
B - B antigen
AB - AB antigen

A

O - AB antibody’s
A - B antibody
B - A antibody
AB - no antibody

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8
Q

Antihuman serum (alpha H) =

A

Antibody against human antigen

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9
Q

Immunogen

A

Immunogen is any agent capable of inducing an immune response and is therefore immunogenic

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10
Q

Soluble proteins are called?

A

Antibodies or Immunoglobins (Ig)

  • Ig make up ~20% of blood protein
  • Ig are produced by B lymphocytes
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11
Q

B cells are made in the ___

A

Bone marrow

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12
Q

T cells are made in the ___

A

Thymus

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13
Q

Epitope (antigenic determinant)

A

Part of an antigen that is bound by an antibody

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14
Q

HHb =

A

Human hemoglobin

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15
Q

Autoimmunity

A

When an individual mounts an immune response against his or her own

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16
Q

Antiserum

A

Fluid component of clotted blood from an immune individual that contains a heterogenous collection of antibodies against the molecule used for immunization

17
Q

Absorption elution

A

ABO typing from dried blood stains

*use antigens present in sample for typing

18
Q

Absorption Inhibition

A

ABO typing from body fluid other then blood

* use antibodies present in sample for typing

19
Q

Polyclonal

A

Antibodies produced by injecting animals with a specific antigen

20
Q

Monoclonal

A

Collection of identical antibodies that interact with a single antigen site

21
Q

Absorption elution

A

ABO typing from dried blood stains

*use antigens present in sample for typing

22
Q

Absorption Inhibition

A

ABO typing from body fluid other then blood

* use antibodies present in sample for typing

23
Q

Polyclonal

A

Antibodies produced by injecting animals with a specific antigen

24
Q

Monoclonal

A

Collection of identical antibodies that interact with a single antigen site

25
Q

Confirmatory test for blood

A

Takayma

not species specific

Forensic Biology (7 decks)

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