Blood Lab Flashcards

(51 cards)

1
Q

Blood has seven functions which include

A
  1. Transporting dissolved gases
  2. Transporting nutrients
  3. Transporting waste
  4. Maintaining pH
  5. Distributing enzymes and hormones
  6. Preventing fluid loss
  7. Carrying toxins
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Blood is divided into two factions

A

Plasma and formed elements

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Plasma contains proteins such as

A

Albumins, globulins, and fibrinogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Plasma contains metabolites such as

A

Lipids, glucose, and amino acids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Overall plasma is composed of

A

Cholesterol, proteins metabolites, nitrogenous wastes, and ions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

The plasma protein albumin is produced by the ___ and comprises of __% total plasma proteins

A

Liver
60%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Albumin function is to

A

Maintain osmotic balance by generating plasma osmotic pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

The two main components of plasma osmotic pressure are

A

Albumin and sodium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Globulins make up __% plasma proteins. It’s two classes are

A

36%
Transport
Immunoglobulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Transport globulins are produced in the ___ and bind to less soluble molecules like ___ and metallic ions like ___

A

Liver
Lipids, hormones (less soluble)
Iron and vitamins (metallic)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Immunoglobulins are known as ____ and are involved in

A

Antibodies
Involved in “humoral” or B-cell mediated immune response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Clotting proteins or fibrinogen comprise of __% plasma proteins

A

4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Formed elements of blood consist of

A

Erythrocytes, leukocytes, and platelets

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Human erythrocytes are filled with ____

A

Hemoglobin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Hemoglobin is

A

The respiratory pigment protein involved in the transport of blood gases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

RBCs pick up O2 from capillaries around the ____ of the lungs

A

Alveolar sacs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

RBCs transport 20% of the body’s CO2 from tissues back to the lungs by

A

Binding it directly to the amino acids of hemoglobin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Leukocytes function in

A

Defense mechanisms for a variety of cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

In response to ____, leukocytes migrate out of capillary blood vessels on a process known as

A

Cytokines
Diapedesis or extravasation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Platelets are cytoplasmic fragments that pinch off from large ____ located at

A

Megakaryocytes
Located at the edge of bone marrow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Antibodies are produced by cells known as

A

B lymphocytes

22
Q

Each B cell demonstrates specificity due to ___ of the antibody

A

The variable region

23
Q

ELISA, or ____ is used in this experiment by

A

Enzyme linked immunosorbent assay
A modified antibody to detect presence of fibrin

24
Q

The presence of the enzyme linked antibody and therefore fibrin will be detected vis

A

The appropriate chromogenic substrate for the enzyme

25
When the enzyme acts upon its substrate, a ____ is formed
Colored product
26
The plates will incubate for ____ minutes at room temperature
45
27
Iron deficiency anemia occurs when
There is insufficient absorption of iron on the diet
28
Pernicious anemia occurs when
There is a deficiency of vitamin B12, usually caused by lack of intrinsic factor
29
Sickle cell anemia arises from a mutation in the
Beta globin chain of hemoglobin
30
Describe the mutation that results in sickle cell anemia
Base change results in insertion of valine instead of glutamic acid
31
Polycythemia refers to
An excess of erythrocytes
32
Polycythemia may develop due to
Temporary lack of O2 due to disease or high altitudes. May be symptomatic of bone marrow disease.
33
Granulocytes leukemia involves ___ while lymphocytic leukemias involves
Descendants of the granulocytes, while lymphocytic leukemias involves the lymphocytes
34
An acute leukemia exhibits a ___ onset while chronic leukemia progresses ____
Rapid onset Slower
35
Infectious mononucleosis is caused by ____ virus and results in
Epstein -Barr Overproduction of agranulocytic leukocytes
36
A person with blood type A will produce ____antibodies
Anti B
37
A person with blood type O produces ____antibodies
Anti A and Anti B
38
A person with blood type AB produces ___antibodies
Neither
39
Agglutination can occur if
Erythrocytes in a blood transfusion contain a different cell-surface antigen than the recipients
40
Blood typing is performed with a sera called ___
Anti sera
41
If agglutination occurs in the suspension that contains the anti A serum, the blood type is
A
42
If agglutination occurs in the suspension that contains Anti B serum, the blood type is
B
43
The absence of agglutination indicates blood type
O
44
If agglutination occurs with both anti A and anti B the blood type is
AB
45
Type O is considered a universal donor because
There are no antigens present
46
Type AB is considered a universal recipient because
Both A and B antigens are present
47
An individual with the D factor will process antigens and is designated
Rh+
48
An individual who lacks the D factor and these antigens is designated
Rh-
49
Anti-Rh antibodies are not usually present in plasma but will be produced upon
Exposure to Rh antigens
50
Erythroblastosis fetallis is
The hemolytic disease where an Rh- mother has a subsequent pregnancy with an Rh+ fetus, which could lead to agglutination
51
Does erythroblastosis fetallis occur if an Rh- fetus is carried to an Rh+ mother? Why or why not?
No because the immune system is not fully developed