Blood/Heart Flashcards
What are the three substances that make up blood?
Erythrocytes, Buffy Coat, and Plasma
What is an erythrocyte
Red blood cell. Not a true cell and make up 44% of blood.
What is the Buffy Coat
Layer of blood that contains leukocytes and platelets (make up 1%)
What is plasma
The liquid ground substance of blood (water and dissolved proteins).
What are the formed elements of blood?
Erythrocytes, leukocytes, and platelets.
What is serum?
When clotting factors are removed from platelets.
What are the three main functions of blood?
Transportation- O2, CO2, nutrients, waste
Regulation- Ph, temperature, fluid levels
Protection- Leukocytes launch immune response and platelets clot.
What are some components of erythrocytes
-No nucleus or organelles
-Bioconcave shape for surface area to increase hemoglobin and to squeeze through capillaries.
-made in red bone marrow
-life expectancy of 120 days
-phagocytized in the spleen and liver
-iron is saved in liver as ferrin until additional production of red blood cells is needed
What is hemoglobin
Molecule that transports oxygen and CO2
-each erythrocyte has 280 mil
-each globin has a non protein heme that contains iron
-each can bind 4 oxygens.
What are the four blood types?
A, B, AB, O
How is blood type determined?
by the presence of surface antigens of erythrocytes.
-A has A, B has B, AB has both, and O has none.
there are dissolved antibodies in plasma
A has anti B, B has anti A, AB has none, O has both
What is the RH blood type?
Whether there is a surface D antigen or not.
-positive has the surface D antigen and no anti D bodies
-negative has no surface D antigens and no anti D antibodies
What happens if you mix blood types?
Agglutination: antibodies bind erythrocytes together forming a clot.
What are some components of leukocytes?
-true cells that undergo mitosis.
-initiate immune response
-largest structure in blood
-can perform diapedisis and chemotaxis
-there are five types
What are the granulocytes?
Neutrophils, Eosinophils, and Basophils
What are the Agranulocytes?
Lymphocytes and Monocytes
What is diapedesis
When cells leave circulatory system and join interstitial fluid
What is chemotaxis?
Ability to detect toxins and head in the direction of
What are some components of platelets?
-small irregular fragment of megakaryote cell.
-first responder in producing blood clot
What is hemopoeisis
Production of blood
-begin with hemocytoblasts (stem cell)
-lymphoid line produces lymphocytes
-myeloid line produces erythrocytes, megakarocytes, and leukocytes
What does the heart do?
Pumps blood to the lungs and body through contractions of the chambers.
What are arteries
Vessels that take blood away from the heart
What are veins?
Vessels that take blood to the heart
What are the great vessels?
arteries and veins that enter and leave the heart
Why is blood flow unidirectional?
There are valves that open and close
What does the right side of the heart do?
Pump blood to the lungs (pulmonary circulation)
What does the left side of the heart do?
Pumps blood to the tissues of the body (Systemic circulation)
What is blood pressure?
Pressure of blood pushing against the vessels
(pressure of pulmonary circulation is low compared to systemic)
-a minimum pressure must be maintained to continue circulation
What is the pericardium
The tough sac that encloses the heart
Fibrous pericardium (outer)
Serous pericardium (inner)
a. outer of serous layer is parietal layer
b. inner of serous layer is visceral layer (becomes epicardium)