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Clin Path > Blood Groups > Flashcards

Blood Groups Flashcards

1
Q

What verifies compatability between donor and recipient

A

Cross-matching

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2
Q

Blood groups are… (3)

A
  • Inheritable
  • Species-specific
  • Immunogenic
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3
Q

T/F - blind transfusions at birth are usually safe

A

True - most animals lack blood group at birth

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4
Q

How many blood groups do horses have

A

7

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5
Q

T/F - horses have a universal donor blood group

A

False - none

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6
Q

Which equine blood groups are most immunogenic

A

EAA

EAQ

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7
Q

Equine blood groups

A

EA……

  • A*
  • C
  • D
    K
  • P
  • Q*
  • U
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8
Q

How can you test a foal for blood group parentage

A

DNA test at hair root

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9
Q

A first mismatched transfusion in a horse is…

A

Well tolerated —> few alloantibodies

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10
Q

How can horses be sensitized to blood groups

A
  1. Prior transfusion
  2. Pregnancy
  3. Vaccine
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11
Q

Future progeny of a sensitized mare are more likely to suffer from what?

A

Neonatal isoerythrolysis

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12
Q

If a sensitized horse is given a mismatched transfusion, what happens?

A

Death

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13
Q

Emergency situation with a horse needing blood. Cannot type. What do you do?

A

Give blood from same breed or close relative

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14
Q

Which blood groups should you not give a horse if you are uncertain of blood type

A

EAA

EAQ

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15
Q

Horse blood donor criteria

A
  • >1000lbs
  • EIA-ve
  • Normal to high Hct
  • Brood mare blood groups must be idnetical to prevent NI
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16
Q

How many blood groups do cows have? How many antigens?

A
  1. 70+antigens
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17
Q

More sensitive bovine blood group

A

J - not part of RBC membrane, antigen reactions

Avoid!

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18
Q

What’s an application of bovine blood testing

A

Parentage

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19
Q
A
20
Q

What happens in a first mis-matched transfusion in a cow

A

Nothing – transfusion reactions are

Unmatched blood results in rapid RBC removal

21
Q

Which canine blood groups are most antigenic? What does mismatching result in?

A

DEA 1.1, 1.2

Hemolysis

22
Q

Which canine blood groups will result in increased removal of transfused RBCs if mis-matched

A

DEA 3, 5, 7

23
Q

Which canine blood groups have alloantibodies

A

DEA 3, 5, 7

24
Q

Which breed are ideal donors? Why?

A

Greyhounds - higher Hct

25
Q

First mis-matched transfusions in dogs are ….

A

Safe

26
Q

T/F Cats have a universal donor

A

False

27
Q

Which feline blood group is most common in USA

A

A

28
Q

Which feline blood group is most common in Europe

A

B

29
Q

Canine blood groups

A

DEA 1 –>8

30
Q

How many blood groups do dogs have

A

8

31
Q

How many bloodgroups do cats have? What are they?

A

3 : A, B, AB

32
Q

What happens if you give a type B cat type A blood?

A

Acute severe transfusion reaction

33
Q

What happens if you give a type A cat type B blood

A

Rapid removal of RBCs

34
Q

Which feline blood group is most antigenic

A

Type B: has most anti-A aggulitins and hemolysins

35
Q

Neonatal isoerythrolysis happens to type _____ kittens born to type _____ cats

A

Type A/AB kittens born to Type B cats

36
Q

C/S neonatal isoerythrolysis in kittens

A

Fatal, fading cat syndrom (subclinical)

37
Q

Donor cat criteria

A
  • FeLV and FIV neg
  • Location: Europe (B) via USA (A)
  • Spp. (breed?) diff
38
Q

Clinical criteria for blood transfusions (3)

A
  • Life-threatening situation
  • Slow progressing anemia (PCV <12%)
  • Rapid progressing anemia (PCV< 20%)
39
Q

Consideration you should make in regards to in-tact females before giving blood donation

A

Transfusion can affect cells of future offspring

40
Q

Lifespan of transfused RBCs in cats, dogs, horses, cows

A

Cats: 5 weeks

Dogs: 3 weeks

Horses: 1 week

Cows: several days

41
Q

How much can an animal donate

A

15 ml/kg every 4 weeks

42
Q

What do you store blood in

A

Acid citrate dextrose

43
Q

Packed RBC samples best for

A

Anemia

44
Q

What are plasma cyroprecipitate products

A

vWF

Factor VIII

45
Q

What are plasma supernatant products

A

Albumin

Factors VII and IX

46
Q

T/F - transfusion reactions only happen if blood groups dont match

A

FALSE

47
Q

Types of transfusion reactions

A
  • Lysis
  • Febrile, non-hemolytic (caused by WBCs)
  • Anaphylaxis
  • Microbe
  • NI
  • DIC
  • Bone marrow suppression
  • Death

Clin Path (11 decks)

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