Blood Donation Flashcards
Minimum age for donation.
17 (without parental consent)
*some states 16 (with parental consent)
Viral Hepatitis
Permanent Deferral
- personal hx after age 11
- Positive HBsAg, anti-HBc, reactive anti-HCV
12 Months
- contact with viral hepatitis
- Incarcerated >72 hours
CJD
Permanent Deferral:
- > 3 months in UK or 5 years total (1980-1996)
- Family Hx
- Bovine Insulin
- Dural Transplant
- Pituitary derived Growth Hormone
HIV
Permanent Deferral:
- HIV+
- Homosex in past 12 months
12 months:
- Healthcare worker exposed to blood of HIV+ pt
Babesiosis & Chagas
Permanent Deferral
Drugs - > 3 years deferral (4)
Permanent Deferral:
- Tegison (etretinate)
- Human Pituitary Growth Hormone
- Bovine Insulin
3 year deferral:
- Soriatane (Acitretin)
Drugs - 24 month (3)
- Erivedge (vismodegib)
- Odomzo (sonidegib)
- Aubagio (teriflunomide)
Drugs - 12 month (2)
- HepB immunoglobulin (HBIG)
- Experimental drug or vaccine
Drugs - 6 month (1)
Dutasteride (avodart)
Drugs - 1 month (2)
- Isotretinoin
- Finasteride
Drugs - 14 days (3)
- Clopidogrel
- Ticlopidine
- Vorapaxar
Drugs - 7 days (5)
- Prasugrel
- Ticagrelor
- Warfarin
- Heparin
- Fondaparinux
Drugs - 3 days (1)
- Piroxicam
Drugs - 2 days (5)
- Deltaparin
- Enoxaparin
- Clabigatran
- Apixaban
- Endoxaban
HTLV-1 infection
Indefinite
Receiving money or drugs for sex
Indefinite
Paying for sex.
12 months
Hx of syphilis, gonorrhea
12 months
Incarceration >72 hours
12 months
Travel to malaria endemic area
12 months
Non-sterile needles (tatoo)
12 months
Lived for >5 years in malaria endemic areas (regardless of prophylaxis)
3 years
Minimum Hb/Hct
12.5/38%
Autologous donor: minimum Hb/Hct
11/33%
Plasmaphoresis: minimum weight
50 kg (110 lbs)
Plasmaphoresis: “frequent” donor program
2 donations/wk; at least 2 days apart
Others: 4 weeks apart
Plateletphersis interval
2/week; at least 2 days apart
<25 in 1 year
Deferral period following single unit of RBCs with platelets and or plasma
8 weeks
Deferral period following double RBC donation by apheresis
16 weeks
Donor Adverse Reactions - Vasovagal Reaction:
- S/S
- Treatment
Donor Adverse Reactions - Vasovagal Reaction:
- Bradycardia, Hypotension, Dizzy, Syncope, Sweating, N/V
- Elevate feet, cold compress to head/neck
Donor Adverse Reactions - Hypovolemia:
- S/S
- Treatment
Donor Adverse Reactions - Hypovolemia:
- Tachycardia w/ Hypotension
- Fluids by mouth or IV
Donor Adverse Reactions - Hyperventilation:
- S/S
- Treatment
Donor Adverse Reactions - Hyperventilation:
- Rapid/Shallow breathing - Hypocapnia (+/- twitching/seizure)
- Breath in paper bag
Donor Adverse Reactions - Citrate effect:
- Only seen in what donors
- MOA
- S/S
- Treatment (mild/severe)
Apheresis donors only
- Hypocalcemia
- Perioral tingling, N/V, arrhythmias, seizures
- Mild - slow infusion
- Severe - Calcium Carbonate (oral)
ABO grouping:
-Forward typing
Donor RBCs w/ anti-A and anti-B reagents
ABO grouping:
-Reverse typing
Donor serum w/ A1 and B reagent RBCs
Rh Type testing is determined by using what?
Anti-D reagent
If anti-D test is negative what is the next step?
-How is this peformed
Test for weak D
-Addition of antihuman globulin (AHG) and extended incubation
The antibody screen is required for what donors? (2)
- History of transfusion
- History Pregnancy
What is the blood type: Forward Grouping -Anti-A - 0 -Anti-B - 0 Reverse Grouping -A cells - 4+ -B cells - 4+
Group O
What is the blood type: Forward Grouping -Anti-A - 4+ -Anti-B - 4+ Reverse Grouping -A cells - 0 -B cells - 0
Group AB
What is the blood type: Forward Grouping -Anti-A - 4+ -Anti-B - 0 Reverse Grouping -A cells - 0 -B cells - 4+
Group A
What is the blood type: Forward Grouping -Anti-A - 0 -Anti-B - 4+ Reverse Grouping -A cells - 4+ -B cells - 0
Group B
What are the required Infectious Diseases tests on donor blood? (8)
- HBsAg
- Anti-HBc
- Anti-HCV
- HCV RNA
- Anti-HIV1/2
- HIV1 RNA
- Anti-HTLV-I/II
- RPR (serologic test for syphilis)
