Blood Disorders

Question 1

Clinical disturbance in anemia occur when Hgb level falls below

Answer 1

7-8g/dl

Question 2

Heinz body presentation

Answer 2

G6PD

Question 3

Normal value of reticulocyte count:

Answer 3

0.5% - 1.5%

Question 4

Marker of ineffective erythropoiesis

Answer 4

Elevated serum LDH

Question 5

Reliable and sensitive index of Vitamin B12 deficiency

Answer 5

Excessive excretion of methylmalonic acid in the urine

Question 6

Most common hematologic disease of infancy and childhood

Answer 6

IRON DEFICIENCY ANEMIA

Question 7

Daily iron requirement

Answer 7

8 – 10 mg of iron

Question 8

Infants who are exclusively breastfed should receive iron supplementation at what age

Answer 8

4 months of age (but usually given at 6 months)

Question 9

Anemia caused solely by inadequate dietary iron usually occurs at what age

Answer 9

6-24 months of age

Question 10

Cooley’s Anemia

Answer 10

Thalassemia Major

Patients cannot maintain oxygenation of their tissues and require regular transfusion to maintain adequate haemoglobin level

Question 11

Release of intracellular uric acid, phosphate and potassium from rapid turnover of malignant cells

Answer 11

Tumor lysis syndrome

Question 12

Rare condition which becomes symptomatic in early infancy; Often with pallor in the neonatal period; short stature, craniofacial deformities, defects of the upper extremities (Triphalangeal thumbs)

Answer 12

CONGENITAL HYPOPLASTIC ANEMIA (DIAMOND-BLACKFAN ANEMIA)

Question 13

Treatment of DIAMOND-BLACKFAN ANEMIA

Answer 13

Corticosteroid

Question 14

Most common acquired red cell aplasia occurring in children

Answer 14

TRANSIENT ERYTHROBLASTOPENIA OF CHILDHOOD (TEC)

Question 15

Transient immunologic suppression of erythropoiesis that frequently follows a viral illness in previously normal child

Answer 15

TRANSIENT ERYTHROBLASTOPENIA OF CHILDHOOD (TEC)