Blood Components

Question 1

Whole blood indications

Answer 1

• Active bleeding (>25 mL blood loss)
• Hemorrhagic shock
• Exchange transfusion
• Both oxygen-carrying capacity and volume expansion are required

Question 2

Packed RBC indications

Answer 2

• Restore oxygen carrying capacity

Question 3

Leukoreduced “Leukopoor” RBC

Answer 3

• Anemia with history of febrile reactions
• To decrease alloimmunization to WBC or HLA antigens or Cytomegalovirus (CMV) transmission

Question 4

Rejuvinated rbc indications

Answer 4

• Regenerate ATP and 2,3-DPG
(both vital in RBC viability)

Question 5

Washed RBC indications

Answer 5

• Anemia with history of febrile reactions
• Paroxysmal Nocturnal Hemoglobinuria (PNH)
• Plasma protein antibodies to reduced allergic reactions (for IgA-deficient patitens)

Question 6

Frozen RBC indications

Answer 6

• Anemia
• Long term storage of rare and/or autologous units

Question 7

Random Donor Platelets

Answer 7

• Thrombocytopenia
• Disseminated Intravascular Coagulation (DIC)
• Platelet Disorders
• Bleeding