Blood Brain Barrier Flashcards

1
Q

The BBB is formed by what 3 structures?

A

Tight Junctions
Basement Membrane
Processes of Astrocytes

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2
Q

Tight junctions are between what?

A

Non-fenestrated capillary endothelial cells

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3
Q

What can freely cross the BBB?

A

Oxygen
Carbon dioxide
Glucose
Amino acids

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4
Q

Lipid soluble substances cross more readily that what?

A

Water soluble substances

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5
Q

What cannot cross the BBB?

A

Bacteria

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6
Q

There are a few specialized regions in the brain where there are fenestrated capillaries and no BBB namely what?

A

Area Postrema

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7
Q

Area Postrema facilitates what

A

Vomiting in response to poisons
Neurohypophysis (posterior pituitary lobe)
Pineal Gland (for secretion of hormones)

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