Blood Flashcards
Blood
Only fluid tissue in body
Connective tissue
Components of blood
Living cells- formed elements
Nonliving matrix- plasma
Oxygen rich blood
Scarlet red
Oxygen poor blood
Dull red
pH must be
7.35-7.44
Blood temperature
100.4°
In a healthy man blood volume is about
5-6 liters or about 6 quarts
Blood makes up ___% of body weight
8%
Blood plasma
90% water
Includes dissolved substances such as: nutrients, salts (electrolytes), respitory gases, hormones, plasma proteins, waste products.
Plasma proteins
Made by liver
Plasma proteins: Albumin
Regulates osmotic pressure
Plasma proteins: clotting proteins
Help to stem blood loss when a blood vessel is injured.
Plasma proteins: antibodies
Help protect the body from pathogens
Formed elements
Erythrocytes: RBC
leukocytes: WBC
Platelets
Cell fragments
Erythrocytes RBCs
Main function: carry oxygen
Erythrocytes RBCs
Biconcave disks Essentially bags of hemoglobin Iron containing protein Binds strongly but reversibly to oxygen Has 4 oxygen binding sites Anucleate (no nucleus) Contains very few organelles
Homeostatic imbalances of Red Blood Cells
Anemia: decrease in the oxygen carrying ability of the blood
Sickle cell anemia (SCA) results from abnormally shaped hemoglobin
Leukocytes or WBC or white blood cells
Crucial in bodies defense against disease
Complete cells with a nucleus and organelles
Can respond to chemicals released by damaged tissues
Leukemia
Abnormal number of leukocytes
Bone marrow becomes cancerous and turns out excess WBC
Types of Leukocytes
Granulocytes
Agranulocytes
Granulocytes
Include neutrophils, eosinophils, and basophils
Agranulocytes
Include lymphocytes and monocytes
List WBCs from most to least abundant
Remember the easy way :)
1) neutrophils
2) lymphocytes
3) monocytes
4) eosinophils
5) basophils
Neutrophils
Acts as phagocytes at active sites of infection
Eosinophils
Found in responses to allergies and parasitic worms
Basophils
Initiate inflammation
Lymphocytes
Play an important role in the immune response
Monocytes
Largest of the white blood cells
Function as macrophages
Important in fighting chronic infection
Platelets
Derived from ruptured multinucleate cells
Needed for the clotting process
Hematopoiesis
Blood cell formation
Occurs in red bone marrow
All blood cells are derived from a common stem cell (hemocytoblast)
Hemostasis
Stoppage of bleeding resulting from a break in a blood vessel
Blood usually clots in
3-6 mins
Thrombus
A clot in an unbroken blood vessel
Can be deadly in areas like the heart
Emblolus
A thrombus that breaks away and floats freely in the blood streak
Can later clog vessels in critical areas like the brain.
Hemophilia
Hereditary bleeding disorder
Normal clotting factors are missing
15-30% of blood causes _______
Loss of over 30% causes shock which can be ________
Weakness
Fatal
Transfusions
The only way to replace blood quickly.
Type O blood
Universal donor
Can only receive O blood
Type AB blood
Universal recipient