Blood 2 Okorie Flashcards

1
Q

what is known as the formation, development and differentiation of blood cells

A

hematopoeses

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2
Q

where are blood cells developed from birth to adult hood

A

yolk sac- liver-spleen- bone marrow

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3
Q

where is blood made for the first 2- 8 weeks prenatally

A

yolk sac

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4
Q

where is blood produced for 6 weeks

A

liver

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5
Q

where is blood produced in the 2nd trimester

A

spleen

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6
Q

where is blood produced in the 3rd trimester

A

bone marrow

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7
Q

where is blood made in the Adult (exclusively)

A

bone marrow

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8
Q

in times of disease, where can the body make blood if not in the bone marrow

A
  • spleen

- liver

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9
Q

what are the 5 things found in bone marrow

A
  • reticular fibers
  • sinusoids
  • cell islands
  • veins
  • arteries
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10
Q

in what bone marrow does active hematopoiesis occur

A

red bone marrow

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11
Q

where does inactive hematopoiesis occurs and you will see fat in reticular fibers?

A

yellow bone marrow

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12
Q

what is the cause of varicose vein

A

leaking valves in the veins

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13
Q

varicose veins are found where

A

lower extremity

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14
Q

why do you give stockings to patients with varicose veins

A

to keep embolus from moving to heart or lungs

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15
Q

idiopathic mwans what

A

unknown cause

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16
Q

how many cells are produced a day

A

10 billion

17
Q

what are the pleuripotent cells that are in low nubers and give rise to
multipotential cells
progenitor cells
precursor cells

A

stem cells

18
Q

what cell lines does the colony forming units in the spleen have? lymphocytes?

A
  • myeloid cell lines

- lymphoid cell lines

19
Q

what are committed to a single cell line, limited self renewal

A

progenitor cells

20
Q

what kind of renewal do precursor cells have

A

none

21
Q

hematopoietic cells will die unless they are exposed to

A

growth factors

22
Q

stem cell factor is known as?

A

steel factor

23
Q

what do hematopoietic growth factors do

A

regulate the differentiation and proliferation of particular progenitor cells.

24
Q

what is pancytopenia

A

decrease in RBC

25
Q

what is the function of RBC’s

A

to carry O2

26
Q

when there are too many RBC in marrow and not enough in circulation (back up) is is?

A

hypercellular marrow

27
Q

what kind of marrow does not have enough RBC in the bone marrow?

A

hypocellular marrow

28
Q

where do RBC go as they get older and they get stuck there

A

the spleen

29
Q

what are RBC broken down into when they are old?

A

bilirubin

30
Q

what are the four types of leukemia and who are they found in

A

ALL- children
AML- children and adults
CML- mostly adults
CLL- only adults