Blood Flashcards
List for solutes of plasma
Proteins glucose, electrolytes, antibodies, hormones, vitamins, and amino acids
What is the solvent of plasma?
Water
What are the formed elements of blood?
Platelets, erythrocytes, and leukocytes
Which formed element has the function of transporting O2 and CO2
Erythrocytes
Which formed element has its primary function protection against foreign antigens?
Leukocytes
Which formed element is important in blood vessel repair?
Platelets
What is the precursor of platelets?
Megakaryocytes
Which leukocytes are Agranulocytes?
Monocytes and lymphocytes
What are the most numerous leukocytes?
Neutrophil
What is the function of the lymphocyte?
Adaptive immune response
What components of blood are in the middle layer of blood centrifuged from a patient?
Leukocytes and platelets
How do you get a hematocrit of a patient?
Red blood cell/total height X 100= % RBC in whole blood
Average hematocrit of an adult?
45%
A—-C—-B
Chemical reaction
Prothrombin—-prothrombin activator—-thrombin
A—-C—-B
Chemical reaction
Fibrinogen—-thrombin—-fibrin
Blood clotting steps
Vascular spasm(vasoconstriction)
COLLAGEN
Platelet plug
PLATELETS
Coagulation
FIBRIN
Create a mesh blood clot that reinforces the platelet plug
Prothrombin
Inactive form of the enzyme thrombin
Once thrombin is chemically produced it catalyzes?
It catalyzes fibrinogen a plasma protein to change into its active form fiber
Fibrin
Create a mesh blood clot that reinforces the platelet plug
Fibrin
Create a mesh blood clot that reinforces the platelet plug
Blood clotting ceases when
the wound is no longer bleeding. This is a positive feedback mechanism.
Extrinsic pathway
Common pathway
Outside wound
Trauma to extravascular cell
Intrinsic pathway
Inside wound
Longer pathway
Steps in hemostasis
Injury— a blood vessel is severed
Vascular spasm — the smooth muscle in the vessel wall contracts near the injury point reducing blood loss
Platelet plug formation— platelets are activated by chemicals released from the injury site and by contact with underlining collagen the platelets become spiked and stick to each other and their wound site
Coagulation— fibrinogen is converted to fibrin which forms a mesh that traps more platelets and erythrocytes sites producing a clot