Blood: 12.4 Questions Flashcards

1
Q

What is the normal platelet count in the adult?

A

130,000 – 400,000/uL

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2
Q

What formed element is responsible for sealing broken blood vessels and sending “messages of help” in large breaks in blood vessels?

A

Thrombocytes

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3
Q

Location:
Where would one normally find platelets?

A

In the bloodstream.

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4
Q

Do platelets have a nucleus?

A

No. They are fragments of a cell.

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5
Q

Which is the smallest – a rbc, a wbc or a platelet?

A

platelet

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6
Q

Platelets secrete vasoconstrictors that cause constriction of ____________.

A

Blood vessels

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7
Q

Platelets can stick together and form _____________ to seal small breaks in injured blood vessels.

A

Platelet plugs

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8
Q

Platelets are fragments from what cell?

A

Megakaryocytes

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9
Q

Hemostasis has three stages. The first stage is ________________ which is constriction within the damaged blood vessel.

A

Vascular spasm

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10
Q

Hemostasis has three stages. The second stage is _____________ which is when platelets stick together to act as a stopper in the blood vessels.

A

Platelet plug

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11
Q

Hemostasis has three stages. The third stage is _____________ which is a complex chain of events that involves many clotting factors. The end goal is to convert fibrinogen to fibrin.

A

coagulation

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12
Q

What does fibrin do in the coagulation process?

A

Forms a sticky net to trap rbcs, wbcs, and platelets to form a clot that allows repair work to fix the damage.

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13
Q

What is the purpose of vascular spasm?

A

Narrows the opening of the blood vessel that is damaged to reduce blood loss.

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14
Q

What is the purpose of platelet plugs?

A

To reduce or stop minor bleeding.

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15
Q

Clotting factors, calcium, prothrombin, thrombin and fibrinogen are all part of the _________________________ process.

A

Coagulation

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16
Q

The absence of clotting factor VIII is the most common cause of:

A

Hemophilia

17
Q

What two types of anticoagulants are used to prevent blood clots from forming?

A

• Coumadin (warfarin)
• Heparin (only given in hospitals)

18
Q

What plasma protein is used in coagulation?

A

Fibrinogen

19
Q

Calcium is needed for coagulation (blood clotting). TRUE or FALSE?

A

True. Thus we have learned four important uses for calcium:
• Used for moving the synaptic vesicle in
neuron transmission
• Used to move the tropomyosin off the
troponin in muscle contraction
• Used to build strong bones and teeth
• Used for blood clotting

20
Q

Most heart attacks and strokes are due to:

A

Thrombosis

21
Q

An abnormal blood clot that develops and remains in an unbroken blood vessel is called a:

22
Q

A piece of a clot that has broken off and traveled in the bloodstream then blocks a different blood vessel is called an:

23
Q

Fibrinogen is converted to fibrin, which forms sticky, web-like threads. What does the “web” trap?

A

RBCs, WBCs and platelets

24
Q

The purpose of ________________ is to form a clot that allows repair work to fix the damage.

A

Coagulation

25
Where are most of the clotting factors produced?
The liver
26
Increased bleeding and bruising may be an indicator of liver disease. This is due to many of the ___________ factors and fibrinogen being produced by the liver.
Clotting