Blood Flashcards

1
Q

What are the 3 main functions of blood

A

Transport
Regulation
Protection

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2
Q

What are red blood cells known as

A

Erythrocytes

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3
Q

What does the blood transport and where from and where to ?
(5)
Oxygen
Carbon dioxide
Nutrients
Hormones
Heat

A

Oxygen from lungs to tissue
carbon dioxide from tissue to lungs
nutrient from digestive system to tissues

Hormones from endocrine cells to target cells

Heat and waste products from cellular respiration

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4
Q

What does the blood regulate (3)

A

Body temperature
Acid base balance (pH)

Water content of tissue

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5
Q

How does blood provides protection

A

Blood Clots to stop bacteria or virus in
White blood cells to fight infection

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6
Q

What makes up whole blood (6)

A

Plasma
Erythrocytes
Leukocytes
Granulocytes
Agranulocytes
Platelets

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7
Q

What does plasma do

A

carrier for proteins through circulation.
body water balance by creating a osmotic pressure in blood vessels.

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8
Q

What happens if the blood is too acidic

A

Homeostatic mechanism will occur
Liver will make more proteins if blood is acidic
Respiratory and renal system will restore the pH of the blood

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9
Q

What does erythrocytes contain and carry

A

Haemoglobin
carry up to 4 oxygen molecules

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10
Q

What are white blood cells called

A

Leukocytes

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11
Q

What do leukocytes do

A

immune response fight invading pathogens

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12
Q

What are the type of granulocytes and what they do (3)

A

Neutrophils- phagocytise bacteria
Eosinophils- allergies kill parasites
Basophils- involved in inflammatory response of body

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13
Q

what are agranulocytes

A

Form plasma cells which produce antibodies

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14
Q

What do monocytes do

A

Phagocytise debris

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15
Q

What do platelets do

A

Involved in blood clotting response

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16
Q

when blood vessels walls rupture due to injury what do platelets form

A

Haemostasis process occur of the platelets stick to area of damage and create a platelet plug that stop bleeding and seals the break

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17
Q

What is haemopoiesis

A

Production of formed elements created in red bone marrow

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18
Q

What is erythropoiesis

A

Production of erythrocytes in the red bone marrow

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19
Q

Why is it important for red blood cell numbers remain within homeostatic range

A

to little red blood cells cause a condition called hypoxia Oxygen deprivation
to many will make blood be too vicious cause harm and damage to cells.

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20
Q

What hormone stimulate the formation of erythrocytes

A

Erythropoietin

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21
Q

Where is erythropoietin released from in the body

22
Q

What happens when the condition of hypoxia occur
( flow diagram)

A

negative homeostatic feed back occurs
Kidney will release erythropoietin which simulate red bone marrow
erythropoiesis increase red blood cell count which increase oxygen

23
Q

What is haemostasis

A

Responses to stop bleeding from a damaged blood vessel

24
Q

What are the three steps of haemostasis

A

Vascular spasm
Platelet plug
blood clotting

25
What is step one of haemostasis
Vascular spasm vasconstriction of blood vessels limit blood loss increase time for the other two steps.
26
What is step 2 of haemostasis
Platelet plug formation Platelets stick together to form a temp plug more platelets are migrate to the area due to chemical messengers - positive feedback system
27
What is step 3 of haemostasis
blood clotting reinforce platelet plug with fibrin thread that bind the platelets together. create a fibrin mesh a blood clot that seals the blood vessels.
28
Why does blood clotting cause a yellow liquid called serum
Blood clots traps blood formed elements the plasma has no clotting proteins
29
How is fibrin mesh formed
In phase 1 the two district pathways intrinsic and extrinsic create a product of prothrombin activators. activators move through phase 2 and 3 which create fibrin mesh
30
Is there chemical reaction in the coagulation process and what is a key ion
yes enzymatic cascade calcium key ion
31
What is a important vitamin in coagulation
Vitamin K needed for 7 of the clotting factors
32
What is haematocrit
The percentage of red blood cells in a blood sample
33
Factors that can affect haematocrit levels
Dehydration Disease conditions cause blood loss Vitamin and mineral deficiency
34
What is a antigen
Anything that the human body may perceive that is foreign
35
What are the eight main group types
A+ A- B+ B- AB+ AB- O+ O-
36
What are the two main groups based on the antigen found on the plasma membrane of red blood cell
ABO Rhesus
37
what do agglutinins do
float in blood plasma reacts against antigens that are not recognised as own the reaction is called agglutination in body immune reaction.
38
if I am blood type A what antigen and antibodies do I have
Antigen- A Antibodies-B
39
if I am blood type b what antigen and antibodies do I have
Antigen- B Antibodies- A
40
if I am blood type AB what antigen and antibodies do I have
Antigen AB Antibodies None
41
if I am blood type O what antigen and antibodies do I have
Antigens none Antibodies A and B
42
What is a transfusion reaction
When incompatible blood type is transfused into a individual.
43
Some one is Rh- and receives Rh+ blood what can happens
body becomes sensitised and produce anti d antibodies no transfusion reaction will occur
44
Can someone who is Rh- can they receive Rh - and Rh+ blood
No only can receive Rh- blood due to they produce antibodies.
45
Why is a pregnant mother blood tested?
To see whether they are Rh - or Rh+ to see whether of a potential transfusion reaction will occur
46
Mothers that is Rh- what is given to them so there is no result of transfusion reaction
anti d immunoglobulins that agglutinate the mother rh factor and prevent sensation
47
What happen if the Mother is Rh - and kept having Rh+ babies
Her anti Rh antibodies would cross the placenta and destroy baby red blood cells
48
Mother is Rh- and kept having Rh+ babies what disease can occur
Haemolytic disease of the newborn where the baby is anaemic and hypoxic and in severe cases can become brain damage or die.
49
What is the universal donor which is blood that can be given to anyone
O negative which is blood that can be given to anyone
50
What is the universal recipient who can receive any blood
AB+
51
What can identify the cells as your and antigen or agglutinogens
Surface of the cell glycolipids and glycoproteins
52
What is agglutinates
Blood clumps together Blood cannot flow through vessels smoothly so become blocked Donor red blood cells will be attacked and ruptured Host red blood cells won't function oxygen around the body Cell tissue will become hypoxia and die