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Block 9 - Reproductive and Endocrine Disease > Block 9 - Drug of Choice > Flashcards

Block 9 - Drug of Choice Flashcards

1
Q

Staphylococcus auerus

A

Vancomycin for MRSA or serious infection w/ unknown susceptibility

Penicillinase-resistant ß-lactams (nafcillin) used pending susceptibility tests

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2
Q

Staphylococcus epidermidids

A

Remove colonized indwelling devices.

Multiple antibiotic resistance common

Drugs. guided by susceptibility testing

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3
Q

Staphylococus saprophyticus

A

TMP-SMX (except in late 3rd trimester pregnancy or nursing)

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4
Q

Streptococcus pyogenes

A

Penicillin G

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5
Q

Streptococcus agalactiae (Group B strep)

A

Penicillin G

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6
Q

Streptococcus pneumoniae

A

Penicillin G if susceptible

3rd generation cephalosporins if resistant

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7
Q

Streptococcus sanguis

A

Penicillin

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8
Q

Enterococcus faecalis

A

Ampicillin

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9
Q

Enterococcus faecium

A

Ampicillin or vancomycin (linezolid or daptomycin if resistant)

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10
Q

Treponema pallidum

A

Benzathine Penicillin G (effective w/ one dose IM or IV)

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11
Q

Leptospira interrogans

A

Penicillin

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12
Q

Borrelia recurrentis

A

Doxycycline or erythromycin

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13
Q

Borrelia burgdorferi

A

Doxycycline, ampicillin or ceftriaxone depending upon disease presentation

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14
Q

Neisseria meningitidis

A

Pencillin

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15
Q

Neisseria gonorrhoeae

A

Ceftriaxone + Azithromycin or Doxycycline

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16
Q

Chlamydia trachomatis

A

Azithromycin - effective with 1 large dose

(Other options require days or weeks of treatment)

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17
Q

Chlamydia pneumoniae

A

Doxycycline

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18
Q

Chlamydia psittaci

A

Doxycycline

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19
Q

Trichomonas vaginalis

A

Metronidazole

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20
Q

Toxoplasma gondii

A

Spiramycin for prenatal infection

Pyrimethamine + sulfadiazine in immunocompromised

21
Q

Yersinia pestis

A

Doxycycline OR streptomycin or gentamicin

22
Q

Brucella sp.

A

Doxycycline PLUS streptomycin or gentamicin

23
Q

Capnocytophaga canimorsus

A

Penicillin plus ß-lactamase inhibitor, or ceftriaxone

24
Q

Francisella tularensis

A

Streptomycin or gentamicin

25
Q

Pasteurella multocida

A

Penicillin plus ß-lactamase inhibitor

26
Q

Trichophyton sp.

A

Skin: Topical azoles, allylamines (terbinafine), tolnaftate.
Oral griseofulvin for tinea capitis

Nails: Oral itraconazole or terbinafine

27
Q

Microsporum sp.

A

Skin: Topical azoles, allylamines (terbinafine), tolnaftate.
Oral griseofulvin for tinea capitis

Nails: Oral itraconazole or terbinafine

28
Q

Epidermophyton floccosum

A

Skin: Topical azoles, allylamines (terbinafine), tolnaftate.
Oral griseofulvin for tinea capitis

Nails: Oral itraconazole or terbinafine

29
Q

Malassezia furfur

A

Azoles

30
Q

Rhizopus sp.

A

Amphotericin B

31
Q

Mucor sp.

A

Amphotericin B

32
Q

Apergillus sp.

A

Itraconazole or voriconazole

33
Q

Pneumocytstis jiroveci

A

Trimethoprim-sulfamethoxazole (TMP-SMX) or pentamidine

34
Q

Candida albicans

A

Skin or mucosal infections: Nystatin, azoles

Candidemia: echinocandins or amphotericin B

35
Q

Candida krusei

A

Echinocandins or amphotericin B

36
Q

Cryptococcus neoformans

A

Non-meningial infections: azoles

Meningitis: Amphotericin B + 5-Flucytosine, then follow with fluconazole.
Fluconazole for prophylaxis

37
Q

Blastomyces dermitidis

A

Itraconazole

38
Q

Histoplasma capsulatum

A

Itraconazole

39
Q

Coccidiodes immitis

A

Itraconazole

40
Q

Paracoccidiodes sp.

A

Itraconazole

41
Q

Sporothrix schenckii

A

Itraconazole

42
Q

Penicillium marneffei

A

Itraconazole

43
Q

Chromoblastomycosis or fungal mycetoma

(conditions with variety of fungal etiologies)

A

Surgical excision followed by prolonged itraconazole

44
Q

Dengue

(Flavivirus)

A

None

45
Q

Yellow Fever

(Flavivirus)

A

None

46
Q

Hantaviruses

(Bunyavirus)

A

None

47
Q

Chickungunya

(Togavirus)

A

None

48
Q

Lassa fever

(Arenavirus)

A

Ribavirin

49
Q

Marburg and Ebola

(Filoviruses)

A

None

Block 9 - Reproductive and Endocrine Disease (22 decks)

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