Block 8 (Neuro) - Online Learning - Neuroimaging Essentials Flashcards
What are the two primary methods of imaging the nervous system?
- MRI
2. CT
Which method of imaging is best for imaging the brain and spinal cord?
MRI
Compare the views obtained from MRI vs. CT.
MRI: axial, sagittal, coronal
CT: axial (need reformatting to obtain other views)
Compare the radiation exposure of MRI vs. CT.
MRI - none
CT - radiation exposure
Compare the scanning times of MRI vs. CT.
MRI: longer scanning time (patient movement degrades images)
CT: shorter scanning time
What are two other limitations of MRI?
Prohibited in presence of pacemakers or certain implanted metal
Tight, enclosed scanner is difficult for claustrophobic patients
Compare the contrast agents used in MRI vs. CT.
MRI: gadolinium
CT: iodine-based
What is highlighted in T1W vs. T2W MRI?
T1W: highlights anatomy
T2W: highlights pathology
How does CSF appear in T1W vs. T2W MRI?
T1W: CSF is dark (low signal)
T2W: CSF is bright (high signal)
What is FLAIR?
Fluid attenuation recovery - like T2W, but the visually distracting high signal of CSF is removed from the images
What are some of the abnormalities detected by neuroimaging (8)?
- Acute intracranial hemorrhage
- Acute cerebral infarction
- Mass effect or edema
- Hydrocephalus
- CNS infection
- Brain tumors
- MS
- Degenerative spine disease
How does acute hemorrhage appear on CT?
Hyperdense (bright or white)
How does hemorrhage appear on CT over time?
As time passes, edema subsides and the hematoma becomes isodense (days 3-15) and then hypodense (dark or black) on CT (after day 15)
How does hemorrhage appear on MRI (T1W/T2W) initially?
T1W: isointense
T2W: bright
How does hemorrhage appear on MRI (T1W/T2W) over time? What leads to this change?
T1W: progresses from isointense to bright to dark (chronic)
T2W: progresses from bright to dark to bright to dark rim (chronic)
Progression of blood (oxy-Hb -> met-Hb -> hemosiderin and ferritin)