Block 8 (Neuro) - Online Learning - Neuroimaging Essentials Flashcards

1
Q

What are the two primary methods of imaging the nervous system?

A
  1. MRI

2. CT

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2
Q

Which method of imaging is best for imaging the brain and spinal cord?

A

MRI

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3
Q

Compare the views obtained from MRI vs. CT.

A

MRI: axial, sagittal, coronal
CT: axial (need reformatting to obtain other views)

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4
Q

Compare the radiation exposure of MRI vs. CT.

A

MRI - none

CT - radiation exposure

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5
Q

Compare the scanning times of MRI vs. CT.

A

MRI: longer scanning time (patient movement degrades images)
CT: shorter scanning time

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6
Q

What are two other limitations of MRI?

A

Prohibited in presence of pacemakers or certain implanted metal

Tight, enclosed scanner is difficult for claustrophobic patients

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7
Q

Compare the contrast agents used in MRI vs. CT.

A

MRI: gadolinium
CT: iodine-based

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8
Q

What is highlighted in T1W vs. T2W MRI?

A

T1W: highlights anatomy
T2W: highlights pathology

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9
Q

How does CSF appear in T1W vs. T2W MRI?

A

T1W: CSF is dark (low signal)
T2W: CSF is bright (high signal)

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10
Q

What is FLAIR?

A

Fluid attenuation recovery - like T2W, but the visually distracting high signal of CSF is removed from the images

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11
Q

What are some of the abnormalities detected by neuroimaging (8)?

A
  1. Acute intracranial hemorrhage
  2. Acute cerebral infarction
  3. Mass effect or edema
  4. Hydrocephalus
  5. CNS infection
  6. Brain tumors
  7. MS
  8. Degenerative spine disease
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12
Q

How does acute hemorrhage appear on CT?

A

Hyperdense (bright or white)

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13
Q

How does hemorrhage appear on CT over time?

A

As time passes, edema subsides and the hematoma becomes isodense (days 3-15) and then hypodense (dark or black) on CT (after day 15)

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14
Q

How does hemorrhage appear on MRI (T1W/T2W) initially?

A

T1W: isointense
T2W: bright

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15
Q

How does hemorrhage appear on MRI (T1W/T2W) over time? What leads to this change?

A

T1W: progresses from isointense to bright to dark (chronic)

T2W: progresses from bright to dark to bright to dark rim (chronic)

Progression of blood (oxy-Hb -> met-Hb -> hemosiderin and ferritin)

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16
Q

How does acute infarction appear on MRI?

A

T2W or FLAIR - high signal (bright)

17
Q

What provides the earliest infarct detection and why?

A

DWI (diffusion weighted imaging) - water diffusion is impaired in an ischemic brain

18
Q

How does acute infarction appear on CT?

A

Hypodensity

19
Q

How does edema appear on CT?

A

Hypodensity

20
Q

How does edema appear on MRI T2W or FLAIR?

A

Increased, high signal intensity

21
Q

What part of the brain is mainly involved in edema?

A

White matter (spares cortical gyri fingers)

22
Q

What is hydrocephalus?

A

Ventricular enlargement without loss of brain tissue, related to impared CSF flow

23
Q

What are the 2 major causes of hydrocephalus and how are they different?

A

Aqueductal stenosis: enlarged lateral and 3rd ventricles (not 4th)

Scarring or blockage of subarachnoid villi: enlarged lateral, 3rd, and 4th ventricles

24
Q

How does an abscess appear?

A

Cavitary, encapsulated lesion (walled-off hole) with surrounding edema; better visualized when the capsule is delineated by contrast

25
Q

Multiple abscesses may mimic ___.

A

Metastatic cancer

26
Q

How does encephalitis or myelitis appear?

A

Focal edema with variable enhancement

27
Q

How does meningitis appear?

A

Leptomeningeal enhancement may occur

28
Q

How do primary brain tumors appear?

A

Solitary, may be irregularly shaped, hemorrhagic or heterogenous

29
Q

How do metastatic brain tumors appear?

A

Solitary or multiple, spherical, at gray-white matter junction

30
Q

How do epidural spinal cord metastases appear?

A

Arise from vertebral bone and encroach upon spinal cord in its canal

31
Q

How does MS appear and what is it seen best with?

A

Plaque lesions in the periventricular white matter, brain stem, or spinal cod; high signal lesions on T2W or FLAIR

32
Q

MS lesions may appear similar to ___.

A

Chronic ischemic white matter lesions

33
Q

What are Dawson’s fingers and when are they seen?

A

Radially arranged lesions in the periventricular area; MS

34
Q

What are some degenerative spine diseases?

A

Spondylosis
Herniated discs
Spinal stenosis

35
Q

If MRI cannot be done, how can degenerative spine diseases be visualized?

A

Spinal CT with intrathecal contrast