Block 5 . . . . Flashcards

1
Q

What viral associated polymerase is associated with negative RNA virus?

A

RNA-dependent RNA polymerase

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2
Q

Negative RNA are?

A

Helical

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3
Q

Positive RNA is

A

Icosahedral

Corona is helical

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4
Q

Negative RNA enveloped

A

“BARF-PO”

Bunya
Arena
Rhabdo
Filo
Paramyx 
Orthomyxo
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5
Q

Positive RNA enveloped

A

Think of being positive as wearing a toga , eating flavor, and drinking corona.

Toga
Flavi
COrona

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6
Q

Positive Naked RNA

A

Pico

Cali

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7
Q

dsRNA

A

Reo “Rotavirus”

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8
Q

Features of naked viruses

A

Tough
contains viral attachment proteins
survives on fomites
Survives the GI tract

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9
Q

Enveloped viruses must be maintained in

A

water

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10
Q

Use VP1 canyon and ICAM

A

Rhinovirus and enterovirus

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11
Q

Prevents binding of gp120 in HIV?

A

Maraviroc

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12
Q

Prevents VP1 from binding to ICAM

A

Pleconaril

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13
Q

Used to treat herpes

A

Acyclovir

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14
Q

Used to treat CMV

A

Gancyclovir

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15
Q

The Valcyclovirs are

A

prodrugs

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16
Q

Interferes with capping and elongation of mRNA.

A

Ribavirin

17
Q

Delayed chain terminator

A

Remdesivir

18
Q

Treats Hep B

A

Entecavir

19
Q

Competitiviely inhibits DNA polymerase. Broad activity against DNA viruses.

A

Cidovir

20
Q

HBV reverse transcriptase

A

Telbivudine

21
Q

HIV reverse transcriptase

A

Zidovudine

22
Q

HIV and HBV reverse transcriptase

A

Adefovir and Tenovir (adenosine)

Lamivudine (cytosine)

23
Q

HIV chain terminators

A

“DAZE”

Didanosine
Abacavir
Zidovudine
Emtricitabine

24
Q

Antiheroes drug that interferes with pyrophosphate binding site

A

Foscarnet

25
Q

What are integrase inhibitors?

A

Keeps DNA from being integrated into host cell (retroviruses)

26
Q

Assembly takes place in cytoplasm for?

A

RNA viruses

27
Q

NA inhibitors

A

osletamivir

zanamivir

peramivir

28
Q

Blocks cap snatching

A

Baloxavir

29
Q

Non segmented RNA

A

Filo, Rhabdo, Paramyxo

30
Q

Segmented RNA

A

Orthomyxo

Arenaviruses

Bunyaviruses

31
Q

Cytoplasmic replication

A
Filo
Arena 
Bunya
Paramyxo
Rhabdo
32
Q

Nuclear replication

A

Borna and Orthomyxo

33
Q

Arbo involves

Allen Diles, Paul Bunyan love flavorful food
They eat it under the arbor

A

Flavi

Toga

Bunya

34
Q

HBsAg

A

Current

35
Q

Current

A

HBsAG

36
Q

Recovered or immune

A

HBsAb

37
Q

HBsAB

A

recovered or immune

38
Q

HBcAb

A

Had or Had (IgM or IgG)

39
Q

Had or had IgM or IgG

A

HBcAB