Block 5 . . . . Flashcards
What viral associated polymerase is associated with negative RNA virus?
RNA-dependent RNA polymerase
Negative RNA are?
Helical
Positive RNA is
Icosahedral
Corona is helical
Negative RNA enveloped
“BARF-PO”
Bunya Arena Rhabdo Filo Paramyx Orthomyxo
Positive RNA enveloped
Think of being positive as wearing a toga , eating flavor, and drinking corona.
Toga
Flavi
COrona
Positive Naked RNA
Pico
Cali
dsRNA
Reo “Rotavirus”
Features of naked viruses
Tough
contains viral attachment proteins
survives on fomites
Survives the GI tract
Enveloped viruses must be maintained in
water
Use VP1 canyon and ICAM
Rhinovirus and enterovirus
Prevents binding of gp120 in HIV?
Maraviroc
Prevents VP1 from binding to ICAM
Pleconaril
Used to treat herpes
Acyclovir
Used to treat CMV
Gancyclovir
The Valcyclovirs are
prodrugs