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Block 5 > Antimicrobials > Flashcards

Antimicrobials Flashcards

1
Q

Binds to 50S

A

Macrolides
Clinda
Chloraphenicol

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2
Q

Binds to 30S

A

Tetracyclines

Aminoglycosides

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3
Q

Hits DNA gyrase

A

Qunolones

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4
Q

Lack bulky side chains

A

Aminopenicillins

(Ex.) Ampicillin

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5
Q

Penicillin resistant penicillins

A

have bulky side chains that prevent inactivation by staph B-lactamases

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6
Q

Carboxypenicillins and Ureidopenicillins

A

Extended spectrum penicillins

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7
Q

Example of Extended spectrum penicillins

A

Piperacillins

Ticarcillins

“pipe and Tike” work against pseudomonas

Grape clusters in the PT office

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8
Q

Cefazolin

A

First gen

covers MSSA

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9
Q

Cefuroxime

A

2nd gen

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10
Q

Ceftriaxone and Ceftazidime

A

Crosses BBB

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11
Q

Cefepime

A

works on pseudomonas aeruginosa

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12
Q

Ceftaroline

A

hits MRSA

“Caroline is turing 5”

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13
Q

Carbepenams do not cover

A

MRSA

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14
Q

Used with IgE allergy

A

Monobactams

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15
Q

Daptomycin

A

bactericidal

  • inhibited by surfactant
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16
Q

Cmax/MIC

A

Daptomycin

17
Q

T>MIC

A

Beta-lactams

18
Q

AUC

A

Vanc

19
Q

Polypeptides

A

used topically for gram positive bacteria

20
Q

Polypeptides MOA

A

inhibit cell wall synthesis

interferes with dephosphorylation and lipid recycling

21
Q

Ethambutol MOA

A

inhibits mycobacterial arabinosyl transferases which are involved in cell wall synthesis

Block 5 (9 decks)

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