Antimicrobials

Question 1

Binds to 50S

Answer 1

Macrolides
Clinda
Chloraphenicol

Question 2

Binds to 30S

Answer 2

Tetracyclines

Aminoglycosides

Question 3

Hits DNA gyrase

Answer 3

Qunolones

Question 4

Lack bulky side chains

Answer 4

Aminopenicillins

(Ex.) Ampicillin

Question 5

Penicillin resistant penicillins

Answer 5

have bulky side chains that prevent inactivation by staph B-lactamases

Question 6

Carboxypenicillins and Ureidopenicillins

Answer 6

Extended spectrum penicillins

Question 7

Example of Extended spectrum penicillins

Answer 7

Piperacillins

Ticarcillins

“pipe and Tike” work against pseudomonas

Grape clusters in the PT office

Question 8

Cefazolin

Answer 8

First gen

covers MSSA

Question 9

Cefuroxime

Answer 9

2nd gen

Question 10

Ceftriaxone and Ceftazidime

Answer 10

Crosses BBB

Question 11

Cefepime

Answer 11

works on pseudomonas aeruginosa

Question 12

Ceftaroline

Answer 12

hits MRSA

“Caroline is turing 5”

Question 13

Carbepenams do not cover

Answer 13

MRSA

Question 14

Used with IgE allergy

Answer 14

Monobactams

Question 15

Daptomycin

Answer 15

bactericidal

• inhibited by surfactant

Question 16

Cmax/MIC

Answer 16

Daptomycin

Question 17

T>MIC

Answer 17

Beta-lactams

Question 18

AUC

Answer 18

Vanc

Question 19

Polypeptides

Answer 19

used topically for gram positive bacteria

Question 20

Polypeptides MOA

Answer 20

inhibit cell wall synthesis

interferes with dephosphorylation and lipid recycling

Question 21

Ethambutol MOA

Answer 21

inhibits mycobacterial arabinosyl transferases which are involved in cell wall synthesis