Block 3 Lecture 2 digestion of carbs Flashcards
what are carbohhydrates broken down into for absorption?
monosaccharides
what are fats broken down into?
fatty acids and glycerol
what is in salivary secretions?
water, ions, salivary amylase and lysozymes
what do mucous cells in the stomach secrete and what is the function of their secretion?
mucous to protect the epithelium from acid secretions
what do parietal cells secrete and what is the function of their secretion?
gastric acid and intrinsic factor, HCL helps with food digestion and intrinsic factor is needed for B12 absoption
what do chief cells secrete and what is the function of their secretion?
pepsinogen the precurser of pepsin which is a proteolytic enzyme
what do enterendocrine cells in the stomach secrete and what is the function of their secretion?
G cells secrete gastrin which is a hormone
what are the different phases of gastric secretion?
cephalic, gastric, intestinal
what is cephalic secretion stimulated by?
stimulated by sight, smell, taste by the vagus nerve
when does gastric secretion occur?
when food is in the stomach
what stimulates gastric secretion from parietal cells? (3)
histamine, gastrin and acetylecholine
how does histamine stimulate parietal cells?
histamine is released by enterochromaffin like cells, it binds to the H2 receptors on parietal cells and activates adenyl cyclase which generates CAMP which activates protein kinases which activates the hydrogen potassium pump
what two ways does gastrin stimulate HCL release?
- gastrin is released from G cells which binds to CCK2 receptors inducing a release of cystolic calcium ions, which activates protein kinases which activates the hydrogen potassium pump
- stimulates ECL cells to secrete histamine
how does acetlycholine induce HCL release?
binds to M3 receptors to increase intracellular callcium, which activates protein kinases which activates the hydrogen potassium pump
what does secretin do?
secreted by the duodemun in response to acid, it inhibits gastric acid secretion