block 3 lecture 5 fat absorption Flashcards
common structure of fats?
triglyceride
what is the structure of triglycerides
3 long chain fatty acids and a glycerol
what is the process to dissolve fats?
emulsification
what stabilizes fat droplets?
bile salts and amphipathic liquids
where are bile salts released from?
gall bladder
why do bile salts coat particles?
to prevent reaggregation
what degrades triglycerides?
lipase
what are the products of lipase digestion?
micelles
where are micelles absorbed?
enterocytes in the jejunum
what are triglycerides broken into?
2 monoglycerides and and fatty acids
what are cholesterol esters broken down into?
cholesterol and fatty acids
what are the sources of lipid degrading enzymes?
lingual lipase, gastric lipase, pancreatic triglyceride lipase
what happens to the lipid products inside the enterocytes?
re-esterified with free fatty acids
reesterified lipids combine with opolipoproteins to form what?
chylomicrons
from enterocytes where are chylomicrons exocytised into?
lacteals
where is bile formed?
liver
where is bile concentrated and stored?
gall bladder
what are the breakdown products of cholesterol?
bile alts
how is cholesterol removed from the body?
stool
how are bile acids made more polar at one end?
they are conjugated to glycine and taurine
where are triglycerides reassembled?
endoplasmic reticulum
why dont chylomicrons enter the blood stream via capillaries?
too big
where do chylomicrons enter the blood stream?
thoracic lymph duct
what shape are HDLs?
disc
what do chylomicrons do?
transport dietry fats from the intestines to tissues
what colour does plasma go after meals?
opaque
where is glycerol transported to for gluconeogenesis?
liver
what does omega 3 do?
controls blood clotting, builds celluler membranes in the brain, enhances brain functions, reduces the risk of cancer/heart disease/diabetes, reduces inflammation
what does omega 6 do?
regulates brain functions, regulates growth and development, hair and skin growth, regulates metabolism, maintains healthy bones, increases inflammation