Block 2 - Sensory and motor neurons Flashcards
What are the 2 types of resistance in neurons?
Longitudinal
Medial
What is the ‘perfect’ neuron comprised of in terms of resistance?
High medial resistance
Low longitudinal resistance
What is decay defined by?
Space constant and time constant
What is space constant? Give an equation
How far the voltage travels
Square root of medial / longitudinal resistance
What is time constant? Give an equation
How fast a voltage travels
Medial resistance x medial capcitance
What is capacitance?
Tendency of the membrane to store charge
How do you increase conduction velocity?
Increase space constant
Decrease time constant
What is the resting potential of mammalians?
-60-70 mA
What are the actions of hyperpolarisation and depolarisation
H - increases potential, so less likely to fire
D - decreases potential, so more likely to fire
How does the sodium-potassium pump work?
For 1 molecule of ATP:
2 x potassium in
3 x sodium out
When does voltage gated ion channels open?
When depolarisation reaches threshold
What are the 3 states of a sodium channel?
Open
Closed
Deactivated
What are the states of a potassium channel?
Open
Closed
Describe the process of an action potential.
Cell membrane depolarises
Threshold reached = sodium channels open
Further depolarisation
Adjacent channels open
Potassium channels open slowly
Sodium channels close and temporarily deactivated
By which feedback is sodium and potassium controlled?
Sodium - negative feedback
Potassium - positive feedback
What does the refractory period ensure?
AP travel in one direction - orthodromic
Which electrode depolarises neurons?
Cathode