Bleeding Ratio/Viscosity Flashcards
Serum Viscosity
Normal range
0.8-1.2
Serum Viscosity
Therapeutic range for stroke prophylaxis
2.0-2.5
Serum Viscosity
Therapeutic range (VTE, PE, patients with atrial fibrillation)
2.0 to 3.0
Serum Viscosity
Therapeutic range for patients at higher risk (prosthetic heart valves)
2.5-3.5
Serum Viscosity
Therapeutic range for patients with lupus anticoagulant
3.0-3.5
Serum Viscosity
Patient at higher risk for bleeding
> 3.6
Activated Partial Thromboplastin Time (Heparin)
Normal range
21-35 seconds
> 70 seconds signifies spontaneous bleeding
Activated Partial Thromboplastin Time (Heparin)
Therapeutic for effectiveness of anticoagulant
2-2.5 times normal range (60-109 seconds)
Variability in reagents
Prothrombin Time (Coumadin)
Normal Range
11-13 sec
Prothrombin Time (Coumadin)
High risk for bleeding into tissue; utilize caution and discuss with interprofessional team
> 25 sec
Anti-Factor Xa Assay (Unfractionated Heparin (UH) and Low Molecular Weight Heparin [LMWH])
Therapeutic ranges of: LMWH
UH
0.5-1.2 IU/mL
0.3-0.7 IU/mL
Anti-Factor Xa Assay (Unfractionated Heparin (UH) and Low Molecular Weight Heparin [LMWH])
Prophylactic ranges of: LMWH
UH
0.25-0.5 IU/mL
0.1-0.4 IU/mL
Due to the D-dimer test’s high sensitivity and poor specificity, a positive test(_____ does not indicate a ___
(>400-500 ng/mL)
VTE
If a patient has a high ____ of developing a VTE, ___ is initiated, regardless of D-dimer test results
pretest probability (Well’s Clinical Prediction Rules)
anticoagulant therapy
____ can result in an elevated D-dimer test
Older age, infections, burns, and heart failure
